16630150

Source:http://linkedlifedata.com/resource/pubmed/id/16630150

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0028429, umls-concept:C0041242, umls-concept:C0656016, umls-concept:C0700624, umls-concept:C0871261, umls-concept:C1280500, umls-concept:C1704632, umls-concept:C1706817, umls-concept:C2911692
pubmed:issue	4
pubmed:dateCreated	2006-4-24
pubmed:abstractText	beta-Tryptase is a multifunctional mast cell serine protease released during mast cell degranulation and tryptase/trypsin inhibitors are a novel potential therapeutic approach for allergic inflammatory diseases.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8906443
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/1-acetyl-N-(4-((aminoiminomethyl)ami..., http://linkedlifedata.com/resource/pubmed/chemical/Allergens, http://linkedlifedata.com/resource/pubmed/chemical/Benzothiazoles, http://linkedlifedata.com/resource/pubmed/chemical/Budesonide, http://linkedlifedata.com/resource/pubmed/chemical/CCL11 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL11, http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2, http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CC, http://linkedlifedata.com/resource/pubmed/chemical/Chemotactic Factors, Eosinophil, http://linkedlifedata.com/resource/pubmed/chemical/Inflammation Mediators, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-5, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-8, http://linkedlifedata.com/resource/pubmed/chemical/Pyrrolidines, http://linkedlifedata.com/resource/pubmed/chemical/Serine Endopeptidases, http://linkedlifedata.com/resource/pubmed/chemical/Thiazoles, http://linkedlifedata.com/resource/pubmed/chemical/Trypsin Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Tryptases, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	0954-7894
pubmed:author	pubmed-author:BarneyP LPL, pubmed-author:BoyceM JMJ, pubmed-author:DurhamS RSR, pubmed-author:ErinE MEM, pubmed-author:HaltonMM, pubmed-author:HigginsL ALA, pubmed-author:JonesR CRC, pubmed-author:LeakerB RBR, pubmed-author:NicholsonG CGC, pubmed-author:ZacharasiewiczAA, pubmed-author:de BoerPP
pubmed:issnType	Print
pubmed:volume	36
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	458-64
pubmed:dateRevised	2007-11-15
pubmed:meshHeading	pubmed-meshheading:16630150-Administration, Intranasal, pubmed-meshheading:16630150-Adult, pubmed-meshheading:16630150-Allergens, pubmed-meshheading:16630150-Benzothiazoles, pubmed-meshheading:16630150-Budesonide, pubmed-meshheading:16630150-Chemokine CCL11, pubmed-meshheading:16630150-Chemokine CCL2, pubmed-meshheading:16630150-Chemokines, CC, pubmed-meshheading:16630150-Chemotactic Factors, Eosinophil, pubmed-meshheading:16630150-Cross-Over Studies, pubmed-meshheading:16630150-Double-Blind Method, pubmed-meshheading:16630150-Eosinophils, pubmed-meshheading:16630150-Female, pubmed-meshheading:16630150-Humans, pubmed-meshheading:16630150-Inflammation Mediators, pubmed-meshheading:16630150-Interleukin-5, pubmed-meshheading:16630150-Interleukin-8, pubmed-meshheading:16630150-Leukocyte Count, pubmed-meshheading:16630150-Male, pubmed-meshheading:16630150-Mast Cells, pubmed-meshheading:16630150-Middle Aged, pubmed-meshheading:16630150-Pyrrolidines, pubmed-meshheading:16630150-Rhinitis, Allergic, Seasonal, pubmed-meshheading:16630150-Serine Endopeptidases, pubmed-meshheading:16630150-Thiazoles, pubmed-meshheading:16630150-Trypsin Inhibitors, pubmed-meshheading:16630150-Tryptases, pubmed-meshheading:16630150-Tumor Necrosis Factor-alpha
pubmed:year	2006
pubmed:articleTitle	Effects of a reversible beta-tryptase and trypsin inhibitor (RWJ-58643) on nasal allergic responses.
pubmed:affiliation	Clinical Studies Unit, National Heart and Lung Institute (NHLI), Imperial College, London, UK.
pubmed:publicationType	Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't