Linked Life Data

16626847

Source:http://linkedlifedata.com/resource/pubmed/id/16626847

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2006-6-5
pubmed:abstractText
In the interaction between Psychiatry and evolutionary theory the force of the impact has not always been in one direction. The Brownes, father and son, had an influence on the development of Darwin's theory at different points in the nineteenth century. The crystallization by Miskolczy in 1933 of the concept that schizophrenia is a disorder that is specific to Homo sapiens is another example. In 1964 the formulation of the central paradox of psychosis by Huxley, Mayr and co-authors and the subsequent critique by Kuttner et al. of the solution Huxley et al. had offered opened up evolutionary approaches to aetiology. Here it is argued that a resolution of this paradox requires identification of the speciation event for modern H. sapiens and elucidation of its neuroanatomical and physiological consequences. It necessitates a saltational account of species transitions and the recognition of species-specific genetic variation. Pursuit of these objectives leads to the hypothesis that speciation events occur selectively on the heterogametic chromosome (the Y in mammals) and are followed by a phase of sexual selection to establish a new specific mate recognition system. In H. sapiens the core component of this system is the capacity for language; the nuclear symptoms of schizophrenia are necessary clues to its neural structure.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0278-5846
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
785-96
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
March 27, 1827 and what happened later--the impact of psychiatry on evolutionary theory.
pubmed:affiliation
Prince of Wales International Centre for SANE Research into Schizophrenia and Depression Warneford Hospital Oxford OX3 7JX, UK. tim.crow@psych.ox.ac.uk
pubmed:publicationType
Journal Article, Review, Historical Article