Linked Life Data

16621470

Source:http://linkedlifedata.com/resource/pubmed/id/16621470

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-5-3
pubmed:abstractText
To investigate the influence of titanium films with nanometre scale topography on protein adsorption and cell growth, three different model titanium films were utilized in the present study. The chemical compositions, surface topographies and wettability were investigated by using X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM) and water contact angle measurement, respectively. The films share the same surface chemistry but exhibit different topographies on a nanometre scale. Thus, they act as model systems for biological studies regarding surface topography effects. The films were obtained by varying the deposition rate and the film thickness, respectively. These films displayed nanometre scale surface roughness (root mean square roughness, R(rms)) from 2 to 21 nm over areas of 50 microm x 50 microm, with different grain sizes at their surfaces. Albumin and fibrinogen adsorption on these model titanium films were performed in this study. Bicinchoninic acid assay was employed to determine the amount of adsorbed protein on titanium film surfaces. No statistically significant differences, however, were observed for either albumin or fibrinogen adsorption between the different groups of titanium films. No statistically significant influence of surface roughness on osteoblast proliferation and cell viability was detected in the present study.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0927-7765
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
136-44
pubmed:dateRevised
2009-10-16
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Does the nanometre scale topography of titanium influence protein adsorption and cell proliferation?
pubmed:affiliation
Institute of Materials Science and Technology (IMT), Friedrich-Schiller-Universität Jena, Löbdergraben 32, D-07743 Jena, Germany. kaiyongcai@hotmail.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't