Source:http://linkedlifedata.com/resource/pubmed/id/16616719
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2006-7-17
|
pubmed:abstractText |
The serotonin transporter (5-HTT) has long been considered likely to play a role in autism. Hyperserotonemia has been consistently found in a proportion of autistic patients, and the use of selective serotonin reuptake inhibitors (SSRIs) can have a positive effect in treating some symptoms of autism. Specific variants of the 5-HTT gene, SLC6A4, especially the insertion-deletion 5-HTTLPR promoter locus, have been found to modulate its expression and transporter function.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0006-3223
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
60
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
186-91
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:16616719-Autistic Disorder,
pubmed-meshheading:16616719-Cohort Studies,
pubmed-meshheading:16616719-Compulsive Behavior,
pubmed-meshheading:16616719-DNA,
pubmed-meshheading:16616719-Genetic Markers,
pubmed-meshheading:16616719-Genotype,
pubmed-meshheading:16616719-Humans,
pubmed-meshheading:16616719-Linkage Disequilibrium,
pubmed-meshheading:16616719-Obsessive-Compulsive Disorder,
pubmed-meshheading:16616719-Phenotype,
pubmed-meshheading:16616719-Polymorphism, Single Nucleotide,
pubmed-meshheading:16616719-Serotonin Plasma Membrane Transport Proteins
|
pubmed:year |
2006
|
pubmed:articleTitle |
Lack of evidence for association of the serotonin transporter gene SLC6A4 with autism.
|
pubmed:affiliation |
Laboratory of Molecular Neuropsychiatry, Department of Psychiatry, Seaver Autism Research Center, Mount Sinai School of Medicine, New York, New York 10029, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|