Source:http://linkedlifedata.com/resource/pubmed/id/16616030
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
2006-4-17
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| pubmed:abstractText |
To investigate ventricular remodeling during long-term right ventricular (RV) pacing after His bundle ablation (HBA) in patients with atrial arrhythmias, a retrospective analysis was performed on echocardiographic data from 45 patients (mean age 57 +/- 11 years) with atrial arrhythmias who underwent HBA and pacemaker implantation (HBA-PI) to control ventricular rate. Echocardiography was performed 1 year before HBA-PI, and up to 7 +/- 2 years of follow-up was conducted. An inverse linear relation was found between the relative increase of left ventricular (LV) end-diastolic diameter (EDD) during long-term RV pacing and LVEDD before HBA-PI (r = -0.61, p<0.001). Patients were divided into 2 groups: those with LVEDDs smaller than the mean LVEDD of 50 mm (group I, 46 +/- 2 mm, n = 28) and those with LVEDDs >50 mm (group II, 56 +/- 4 mm, n = 17). Before HBA-PI, patients in group I had significantly smaller LV weights (167 +/- 44 vs 238 +/- 56 g) and LV end-systolic diameters (30 +/- 2 vs 42 +/- 7 mm) and higher LV ejection fractions (64 +/- 5% vs 49+/- 12%) than those in group II. In group I, long-term RV pacing increased LVEDD, LV end-systolic diameter, LV weight, and left atrial diameter; increased mitral regurgitation; and decreased the LV ejection fraction and LV fractional shortening. No significant changes were observed during long-term RV pacing in group II. In conclusion, long-term RV pacing after HBA adversely affects LV structure and function in patients with initially normal LV dimensions and function.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Apr
|
| pubmed:issn |
0002-9149
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
97
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1223-7
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| pubmed:dateRevised |
2007-11-15
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| pubmed:meshHeading |
pubmed-meshheading:16616030-Arrhythmias, Cardiac,
pubmed-meshheading:16616030-Bundle of His,
pubmed-meshheading:16616030-Cardiac Pacing, Artificial,
pubmed-meshheading:16616030-Catheter Ablation,
pubmed-meshheading:16616030-Diastole,
pubmed-meshheading:16616030-Echocardiography,
pubmed-meshheading:16616030-Female,
pubmed-meshheading:16616030-Follow-Up Studies,
pubmed-meshheading:16616030-Heart Ventricles,
pubmed-meshheading:16616030-Humans,
pubmed-meshheading:16616030-Hypertrophy, Left Ventricular,
pubmed-meshheading:16616030-Male,
pubmed-meshheading:16616030-Middle Aged,
pubmed-meshheading:16616030-Mitral Valve Insufficiency,
pubmed-meshheading:16616030-Pacemaker, Artificial,
pubmed-meshheading:16616030-Retrospective Studies,
pubmed-meshheading:16616030-Stroke Volume,
pubmed-meshheading:16616030-Systole,
pubmed-meshheading:16616030-Ventricular Dysfunction, Right,
pubmed-meshheading:16616030-Ventricular Function, Left,
pubmed-meshheading:16616030-Ventricular Remodeling
|
| pubmed:year |
2006
|
| pubmed:articleTitle |
Ventricular remodeling during long-term right ventricular pacing following His bundle ablation.
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| pubmed:affiliation |
Department of Cardiology, Cardiovascular Research Institute Maastricht, University Hospital Maastricht, Maastricht, The Netherlands. k.vernooy@fys.unimaas.nl
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|