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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2006-5-4
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pubmed:abstractText |
Thalidomide is an immunomodulatory agent, which arrests angiogenesis. The mechanism of anti-angiogenic activity of thalidomide is not fully understood. As nitric oxide is involved in angiogenesis, we speculate a cross-talk between thalidomide and nitric oxide signaling pathway to define angiogenesis. The aim of present study is to understand the mechanistic aspects of thalidomide-mediated attenuation of angiogenesis induced by nitric oxide at the cellular level.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-10384139,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-10506758,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-11753617,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-12360276,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-12402158,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-12423428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-12507958,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-12533164,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-12759249,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-14555685,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-15221409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-15256481,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-15501442,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-15534002,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-15576902,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-15679116,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-15710258,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-15718159,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-15868099,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/16584574-9859910
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2121
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
17
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16584574-Actins,
pubmed-meshheading:16584574-Angiogenesis Inhibitors,
pubmed-meshheading:16584574-Animals,
pubmed-meshheading:16584574-Biopolymers,
pubmed-meshheading:16584574-Cells, Cultured,
pubmed-meshheading:16584574-Chick Embryo,
pubmed-meshheading:16584574-Cytoskeleton,
pubmed-meshheading:16584574-Endothelial Cells,
pubmed-meshheading:16584574-Endothelium, Vascular,
pubmed-meshheading:16584574-Humans,
pubmed-meshheading:16584574-Neovascularization, Physiologic,
pubmed-meshheading:16584574-Nitric Oxide,
pubmed-meshheading:16584574-Nitric Oxide Donors,
pubmed-meshheading:16584574-S-Nitroso-N-Acetylpenicillamine,
pubmed-meshheading:16584574-Thalidomide,
pubmed-meshheading:16584574-Umbilical Veins,
pubmed-meshheading:16584574-Wound Healing,
pubmed-meshheading:16584574-Yolk Sac
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pubmed:year |
2006
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pubmed:articleTitle |
Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells.
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pubmed:affiliation |
Vascular Biology Lab, AU-KBC Research Centre, Anna University, Chennai, India. Tamilarasan@au-kbc.org
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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