Source:http://linkedlifedata.com/resource/pubmed/id/16581163
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
20
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pubmed:dateCreated |
2006-5-8
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pubmed:abstractText |
We evaluated in a prospective study the immune response of naïve subjects to a single dose of inactivated Hepatitis A vaccine. Ninety-seven percent of the vaccinees sero-converted 1 month after vaccination and 93% were still positive 2 years later. All of the vaccinees had a strong booster response 2 years after the single dose. Avaxim was more immunogenic than Vaqta for the primary dose (p = 0.01 for sero-positivity, p<0.001 for antibody level) but no differences were found after boosting with Avaxim. Performance of intense physical activity during the first month after a single vaccine dose was associated with lower antibody levels (p = 0.004). This study indicates that a single dose of inactivated HAV vaccine elicits protective immune memory for at least 2 years.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0264-410X
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pubmed:author |
pubmed-author:AmbarRuhamaR,
pubmed-author:AviramLisaL,
pubmed-author:BalicerRanR,
pubmed-author:CohenDaniD,
pubmed-author:DerazneEstelaE,
pubmed-author:EpsteinYoramY,
pubmed-author:GillisDavidD,
pubmed-author:GrottoItamarI,
pubmed-author:HeledYuvalY,
pubmed-author:HuertaMichaelM,
pubmed-author:KayoufRaidR,
pubmed-author:KlementEyalE,
pubmed-author:OrrNadavN,
pubmed-author:SelaTamarT
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4328-32
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pubmed:meshHeading | |
pubmed:year |
2006
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pubmed:articleTitle |
Long-term immunity in young adults after a single dose of inactivated Hepatitis A vaccines.
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pubmed:affiliation |
Center for Vaccine Development and Evaluation, IDF, Israel. naorr@012.net.il
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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