Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2006-5-26
pubmed:abstractText
Gilead, Zvee (University of Pennsylvania, Philadelphia), and Harold S. Ginsberg. Characterization of a tumor-like antigen in type 12 and type 18 adenovirus-infected cells. J. Bacteriol. 90:120-125. 1965.-An antigen that reacts with antibody from type 12 adenovirus tumor-bearing hamsters was identified in extracts of KB cells infected with type 12 or 18 adenovirus. In contrast, viral structural proteins separated by chromatography on diethylaminoethyl-cellulose did not react with the sera from tumorous hamsters. The tumorlike (T) antigen in infected cells was found to be smaller than the viral structural antigens and, therefore, could be separated from them by centrifugation in a linear sucrose gradient. Investigation of the production of the T antigen in virus-infected cells further distinguished it from viral structural proteins by the following properties: (i) the T antigen was first detected 3 to 4 hr after infection, whereas viral antigens were synthesized 17 to 20 hr after infection; and (ii) the T antigen was produced when deoxyribonucleic acid (DNA) biosynthesis was inhibited by 5-fluorodeoxyuridine (10(-6)m), but viral proteins were not synthesized in the absence of viral DNA replication.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-13293190, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-13675766, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-13694445, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-13767412, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-13785230, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-13893423, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-13905041, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-13910995, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-13955470, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14033129, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14060660, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14074393, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14074394, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14163330, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14166590, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14171456, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14194601, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14212121, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14231431, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14231432, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14381511, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14409793, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-14907713, http://linkedlifedata.com/resource/pubmed/commentcorrection/16562005-16590300
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Jul
pubmed:issn
0021-9193
pubmed:author
pubmed:issnType
Print
pubmed:volume
90
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
120-5
pubmed:dateRevised
2009-11-18
pubmed:year
1965
pubmed:articleTitle
Characterization of a Tumorlike Antigen in Type 12 and Type 18 Adenovirus-Infected Cells.
pubmed:affiliation
Department of Microbiology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
pubmed:publicationType
Journal Article