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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-3-21
pubmed:abstractText
The aim of this study was to retrospectively analyze brain magnetic resonance imaging (MRI) findings in patients who developed neurologic complications after liver and kidney transplantation. The results in 216 organ transplant recipients, who had brain MRI were evaluated retrospectively. We performed 187 brain MRI on kidney recipients and 29 liver recipients. Neuroradiologic findings were classified in three groups: group 1 findings were related to transplantation; group 2 findings, to chronic parenchymal disease; and group 3 to neither transplantation nor chronic parenchymal disease. In group 1, six patients (20.6%) after liver and three (1.6%) after kidney transplantation had posterior reversible encephalopathy syndrome; two patients (1.1%) after renal and one (3.4%) after liver transplantation had tuberculosis granulomas; one patient (0.5%) after renal transplantation had osmotic demyelination syndrome; one patient (0.5%) had a Nocardia abcess and one (0.5%) focal cerebritis after renal transplantation. Among group 2, 38 patients (20.3%) had brain atrophy; 37 (20%), white matter changes; 3 (1.6%), sinus thrombosis; 8 (4.3%), lacunar infarct; 1 (0.5%), had renal osteodystrophy in the cranial bones; and 4 (2.2%), had intracranial hemorrhage secondary to end-stage renal disease. Brain atrophy in nine patients (31%), hyperintensity in the globus pallidus on T1-weighted MR images owing to manganese deposits in nine patients (31%), hyperintensity in basal ganglia on T2-weighted MR images owing to copper depositions in one patient (3.4%) were seen secondary to chronic liver disease. In group 3, three patients (1.6%) had intracranial lipomas; one (0.5%), mesial temporal sclerosis; and one (0.5%), an anterior cerebral artery aneurysm in renal transplant patients. Periventricular and subcortical white matter hyperintensities were observed on T2-weighted MR images in six liver transplant patients (20.7%). Neurologic complications after organ transplantation may be secondary to transplantation itself, to chronic parenchymal disease, or to neither transplantation nor chronic parenchymal disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0041-1345
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
611-8
pubmed:meshHeading
pubmed-meshheading:16549189-Adult, pubmed-meshheading:16549189-Atrophy, pubmed-meshheading:16549189-Brain, pubmed-meshheading:16549189-Brain Diseases, pubmed-meshheading:16549189-Child, pubmed-meshheading:16549189-Female, pubmed-meshheading:16549189-Humans, pubmed-meshheading:16549189-Kidney Diseases, pubmed-meshheading:16549189-Kidney Transplantation, pubmed-meshheading:16549189-Liver Diseases, pubmed-meshheading:16549189-Liver Failure, pubmed-meshheading:16549189-Liver Transplantation, pubmed-meshheading:16549189-Living Donors, pubmed-meshheading:16549189-Magnetic Resonance Imaging, pubmed-meshheading:16549189-Male, pubmed-meshheading:16549189-Nervous System Diseases, pubmed-meshheading:16549189-Postoperative Complications, pubmed-meshheading:16549189-Retrospective Studies, pubmed-meshheading:16549189-Tissue Donors
pubmed:year
2006
pubmed:articleTitle
Evaluation of neurologic complications by brain MRI in kidney and liver transplant recipients.
pubmed:affiliation
Ba?kent University, Faculty of Medicine, Department of Radiology, Ankara, Turkey. muhtesem@baskent-ank.edu.tr
pubmed:publicationType
Journal Article