Source:http://linkedlifedata.com/resource/pubmed/id/16540901
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2006-3-16
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pubmed:abstractText |
Nasal polyposis (NP) is a chronic inflammatory disease of the upper respiratory tract. The pathophysiology is unknown but has been shown to be multifactorial. Free radical-mediated damage has been implicated in the pathogenesis of NP. Superoxide dismutases (SODs) are the first and the most important line of antioxidant enzyme defense against reactive oxygen species. Moreover, isozymes of the SOD family are critical for modulating the activity of nitric oxide, a gaseous free radical that is believed to play roles in the physiology and pathology of respiratory tracts. However, the expression profile of SOD isoforms in NP remains unclear. We aimed to investigate the expression profile of the SOD isoforms in nasal polyps from nonallergic patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0023-852X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
116
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
417-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16540901-Adult,
pubmed-meshheading:16540901-Aged,
pubmed-meshheading:16540901-Blotting, Western,
pubmed-meshheading:16540901-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16540901-Female,
pubmed-meshheading:16540901-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:16540901-Genetic Markers,
pubmed-meshheading:16540901-Humans,
pubmed-meshheading:16540901-Isoenzymes,
pubmed-meshheading:16540901-Male,
pubmed-meshheading:16540901-Middle Aged,
pubmed-meshheading:16540901-Nasal Polyps,
pubmed-meshheading:16540901-RNA, Messenger,
pubmed-meshheading:16540901-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16540901-Superoxide Dismutase
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pubmed:year |
2006
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pubmed:articleTitle |
Altered expression profile of superoxide dismutase isoforms in nasal polyps from nonallergic patients.
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pubmed:affiliation |
Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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