| pubmed-article:16539746 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C0006142 | lld:lifeskim |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C1533685 | lld:lifeskim |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C0021102 | lld:lifeskim |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C1517499 | lld:lifeskim |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C1517564 | lld:lifeskim |
| pubmed-article:16539746 | lifeskim:mentions | umls-concept:C0879457 | lld:lifeskim |
| pubmed-article:16539746 | pubmed:dateCreated | 2006-5-18 | lld:pubmed |
| pubmed-article:16539746 | pubmed:abstractText | HSVtk/ganciclovir (GCV) gene therapy has been extensively studied in tumors and relies largely on the gene expression of HSVtk. Most studies, however, have failed to demonstrate any significant benefit of a controlled gene expression strategy in cancer treatment. The Tet-On system is commonly used to regulate gene expression following Dox induction. We have evaluated the antitumor effect of HSVtk/ganciclovir gene therapy under Tet-On regulation by means of adeno-associated virus-2 (AAV-2)-mediated HSVtk gene transfer with direct intratumoral injections in mice bearing breast cancer tumors. | lld:pubmed |
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| pubmed-article:16539746 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16539746 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16539746 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:16539746 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16539746 | pubmed:issn | 1471-2407 | lld:pubmed |
| pubmed-article:16539746 | pubmed:author | pubmed-author:ChenQianQ | lld:pubmed |
| pubmed-article:16539746 | pubmed:author | pubmed-author:HuWei-XinWX | lld:pubmed |
| pubmed-article:16539746 | pubmed:author | pubmed-author:LiZi-BoZB | lld:pubmed |
| pubmed-article:16539746 | pubmed:author | pubmed-author:ZengZhao-JunZ... | lld:pubmed |
| pubmed-article:16539746 | pubmed:author | pubmed-author:LuoSai-QunSQ | lld:pubmed |
| pubmed-article:16539746 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:16539746 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:16539746 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16539746 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16539746 | pubmed:pagination | 66 | lld:pubmed |
| pubmed-article:16539746 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:16539746 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16539746 | pubmed:articleTitle | Recombinant AAV-mediated HSVtk gene transfer with direct intratumoral injections and Tet-On regulation for implanted human breast cancer. | lld:pubmed |
| pubmed-article:16539746 | pubmed:affiliation | Molecular Biology Research Center, Xiangya Medical College, Central South University, Changsha, Hunan 410078, PR China. Lzb1022@hotmail.com | lld:pubmed |
| pubmed-article:16539746 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16539746 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16539746 | lld:pubmed |
