rdf:type |
|
lifeskim:mentions |
umls-concept:C0005684,
umls-concept:C0008115,
umls-concept:C0015923,
umls-concept:C0033413,
umls-concept:C0035647,
umls-concept:C0205245,
umls-concept:C0936012,
umls-concept:C1539477,
umls-concept:C1706006,
umls-concept:C1710133,
umls-concept:C1882417
|
pubmed:issue |
4
|
pubmed:dateCreated |
2006-3-15
|
pubmed:abstractText |
FAS and FASLG together initiate apoptosis, which prevents tumor development. FAS and FASLG polymorphisms in the promoter regions can alter the transcriptional activities and thus alter risk of cancer. We hypothesized that the FAS -1377G>A, -670A>G, and FASLG -844T>C polymorphisms are associated with risk of bladder cancer.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1744-6872
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
245-51
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:16538171-Adult,
pubmed-meshheading:16538171-Aged,
pubmed-meshheading:16538171-Alleles,
pubmed-meshheading:16538171-Carcinoma, Transitional Cell,
pubmed-meshheading:16538171-Case-Control Studies,
pubmed-meshheading:16538171-China,
pubmed-meshheading:16538171-Confidence Intervals,
pubmed-meshheading:16538171-Fas Ligand Protein,
pubmed-meshheading:16538171-Female,
pubmed-meshheading:16538171-Genetic Variation,
pubmed-meshheading:16538171-Haplotypes,
pubmed-meshheading:16538171-Humans,
pubmed-meshheading:16538171-Male,
pubmed-meshheading:16538171-Membrane Glycoproteins,
pubmed-meshheading:16538171-Middle Aged,
pubmed-meshheading:16538171-Molecular Epidemiology,
pubmed-meshheading:16538171-Odds Ratio,
pubmed-meshheading:16538171-Polymorphism, Genetic,
pubmed-meshheading:16538171-Promoter Regions, Genetic,
pubmed-meshheading:16538171-Risk Factors,
pubmed-meshheading:16538171-Tumor Necrosis Factors,
pubmed-meshheading:16538171-Urinary Bladder Neoplasms
|
pubmed:year |
2006
|
pubmed:articleTitle |
Functional polymorphisms in the promoter regions of the FAS and FAS ligand genes and risk of bladder cancer in south China: a case-control analysis.
|
pubmed:affiliation |
Department of Molecular Genetic Toxicology, Nanjing Medical University, 140 Hanzhong Road, Nanjing 210029, China.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|