|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0015672,
umls-concept:C0030705,
umls-concept:C0066677,
umls-concept:C0087111,
umls-concept:C0231448,
umls-concept:C0360105,
umls-concept:C0917799,
umls-concept:C1269683,
umls-concept:C1293122,
umls-concept:C2603343,
umls-concept:C2911696
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2006-3-7
|
|
pubmed:abstractText |
Many patients with major depressive disorder (MDD) treated with selective serotonin reuptake inhibitors have residual symptoms (eg, persistent fatigue, excessive sleepiness) despite an overall antidepressant response. Placebo-controlled studies indicate that modafinil, a wake-promoting agent, may relieve residual symptoms.
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|
pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1092-8529
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
93-102
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:16520686-Adolescent,
pubmed-meshheading:16520686-Adult,
pubmed-meshheading:16520686-Aged,
pubmed-meshheading:16520686-Benzhydryl Compounds,
pubmed-meshheading:16520686-Central Nervous System Stimulants,
pubmed-meshheading:16520686-Depressive Disorder, Major,
pubmed-meshheading:16520686-Disorders of Excessive Somnolence,
pubmed-meshheading:16520686-Double-Blind Method,
pubmed-meshheading:16520686-Drug Administration Schedule,
pubmed-meshheading:16520686-Drug Synergism,
pubmed-meshheading:16520686-Drug Therapy, Combination,
pubmed-meshheading:16520686-Fatigue,
pubmed-meshheading:16520686-Female,
pubmed-meshheading:16520686-Humans,
pubmed-meshheading:16520686-Male,
pubmed-meshheading:16520686-Middle Aged,
pubmed-meshheading:16520686-Paroxetine,
pubmed-meshheading:16520686-Serotonin Uptake Inhibitors,
pubmed-meshheading:16520686-Sertraline
|
|
pubmed:year |
2006
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|
pubmed:articleTitle |
Modafinil augmentation of SSRI therapy in patients with major depressive disorder and excessive sleepiness and fatigue: a 12-week, open-label, extension study.
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|
pubmed:affiliation |
Division of Adult Academic Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. thaseme@upmc.edu
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|
