rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2006-3-28
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pubmed:abstractText |
The natural history of gastrointestinal stromal tumor (GIST) has been revolutionized by imatinib mesylate (imatinib) therapy. Before imatinib, Bcl-2 expression in GIST was associated with a worse prognosis or added no additional prognostic value. To the authors' knowledge, the current study is the first to evaluate Bcl-2 expression in pre-imatinib GIST tissue samples as a prognostic marker of progression-free survival (PFS) time in patients treated with imatinib.
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pubmed:grant |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0008-543X
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pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2006 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
1
|
pubmed:volume |
106
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1617-23
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16518826-Adult,
pubmed-meshheading:16518826-Aged,
pubmed-meshheading:16518826-Aged, 80 and over,
pubmed-meshheading:16518826-Disease Progression,
pubmed-meshheading:16518826-Disease-Free Survival,
pubmed-meshheading:16518826-Female,
pubmed-meshheading:16518826-Gastrointestinal Stromal Tumors,
pubmed-meshheading:16518826-Humans,
pubmed-meshheading:16518826-Immunohistochemistry,
pubmed-meshheading:16518826-Male,
pubmed-meshheading:16518826-Middle Aged,
pubmed-meshheading:16518826-Piperazines,
pubmed-meshheading:16518826-Prognosis,
pubmed-meshheading:16518826-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:16518826-Pyrimidines,
pubmed-meshheading:16518826-Retrospective Studies,
pubmed-meshheading:16518826-Tumor Markers, Biological
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pubmed:year |
2006
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pubmed:articleTitle |
Expression of Bcl-2 in gastrointestinal stromal tumors: correlation with progression-free survival in 81 patients treated with imatinib mesylate.
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pubmed:affiliation |
Department of Sarcoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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