|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2006-3-3
|
|
pubmed:abstractText |
The alpha2A-adrenergic receptor (ADRA2A) plays a central role in the regulation of systemic sympathetic activity and hence cardiovascular responses such as heart rate and blood pressure. The objectives of this study were to systematically search for variants in the ADRA2A gene, to define the gene's haplotype structure, and to examine potential functional effects of these variants.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0009-9236
|
|
pubmed:author |
pubmed-author:DawsonElliott PEP,
pubmed-author:EschJ FJF,
pubmed-author:HarrisPaul APA,
pubmed-author:IhriePatrickP,
pubmed-author:JiangLanL,
pubmed-author:KurnikDanielD,
pubmed-author:McMunnCharaC,
pubmed-author:MuszkatMordechaiM,
pubmed-author:SofoworaGbenga GGG,
pubmed-author:SolusJosephJ,
pubmed-author:SteinC MichaelCM,
pubmed-author:WilliamsScott MSM,
pubmed-author:WoodAlastair J JAJ,
pubmed-author:XieHong-GuangHG
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
79
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
173-85
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:16513442-Adult,
pubmed-meshheading:16513442-African Continental Ancestry Group,
pubmed-meshheading:16513442-Alleles,
pubmed-meshheading:16513442-Blood Pressure,
pubmed-meshheading:16513442-DNA Primers,
pubmed-meshheading:16513442-European Continental Ancestry Group,
pubmed-meshheading:16513442-Female,
pubmed-meshheading:16513442-Gene Frequency,
pubmed-meshheading:16513442-Genetic Variation,
pubmed-meshheading:16513442-Haplotypes,
pubmed-meshheading:16513442-Heart Rate,
pubmed-meshheading:16513442-Humans,
pubmed-meshheading:16513442-Linkage Disequilibrium,
pubmed-meshheading:16513442-Male,
pubmed-meshheading:16513442-Norepinephrine,
pubmed-meshheading:16513442-Receptors, Adrenergic, alpha-2,
pubmed-meshheading:16513442-Sympathetic Nervous System,
pubmed-meshheading:16513442-United States
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Variations in the alpha2A-adrenergic receptor gene and their functional effects.
|
|
pubmed:affiliation |
Department of Medicine, Division of Clinical Pharmacology, Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, TN 37232-6606, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|
