The current recommended therapy for diffuse coccidioidal pneumonia involves initial treatment with amphotericin B deoxycholate or high-dose fluconazole, followed by an azole after clinical improvement. Amphotericin B is more frequently used as initial therapy if the patient's deterioration is rapid.
Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seongbuk-gu, Seoul 136-705, Republic of Korea. pugae1@hanmail.net