|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2006-2-15
|
|
pubmed:abstractText |
Brain natriuretic peptide (BNP) blunts hypoxic pulmonary hypertension in animal models, but its acute hemodynamic effects in patients with pulmonary arterial hypertension (PAH) are not known. The aim of this study was to determine if human B-type natriuretic peptide is a safe and efficacious pulmonary vasodilator in patients with PAH and if the pulmonary hemodynamic effects are potentiated by phosphodiesterase inhibition.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0012-3692
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
129
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
417-25
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:16478861-Administration, Inhalation,
pubmed-meshheading:16478861-Administration, Oral,
pubmed-meshheading:16478861-Adult,
pubmed-meshheading:16478861-Aged,
pubmed-meshheading:16478861-Aged, 80 and over,
pubmed-meshheading:16478861-Blood Pressure,
pubmed-meshheading:16478861-Drug Synergism,
pubmed-meshheading:16478861-Drug Therapy, Combination,
pubmed-meshheading:16478861-Epoprostenol,
pubmed-meshheading:16478861-Female,
pubmed-meshheading:16478861-Humans,
pubmed-meshheading:16478861-Hypertension, Pulmonary,
pubmed-meshheading:16478861-Infusions, Intravenous,
pubmed-meshheading:16478861-Male,
pubmed-meshheading:16478861-Middle Aged,
pubmed-meshheading:16478861-Natriuretic Peptide, Brain,
pubmed-meshheading:16478861-Nitric Oxide,
pubmed-meshheading:16478861-Phosphodiesterase Inhibitors,
pubmed-meshheading:16478861-Piperazines,
pubmed-meshheading:16478861-Pulmonary Circulation,
pubmed-meshheading:16478861-Purines,
pubmed-meshheading:16478861-Sulfones,
pubmed-meshheading:16478861-Vascular Resistance,
pubmed-meshheading:16478861-Vasodilator Agents
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Pulmonary hemodynamic responses to brain natriuretic peptide and sildenafil in patients with pulmonary arterial hypertension.
|
|
pubmed:affiliation |
Division of Pulmonary, Sleep and Critical Care Medicine, Rhode Island Hospital and Brown Medical School, Providence, RI 02903, USA. james_klinger@brown.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
