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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-2-13
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pubmed:abstractText |
Recently described genome-wide approaches robustly detect many candidate genes that are regulated by DNA methylation, but many of these genes do not represent important targets for functional inactivation. Here we used a microarray-based strategy to identify biologically relevant genes associated with epigenetic silencing in pancreatic cancer.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules, Neuronal,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Matrix Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Luciferases,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/Serine Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/reelin protein
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
548-65
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16472607-Cell Adhesion Molecules, Neuronal,
pubmed-meshheading:16472607-DNA Methylation,
pubmed-meshheading:16472607-DNA Primers,
pubmed-meshheading:16472607-Extracellular Matrix Proteins,
pubmed-meshheading:16472607-Gene Deletion,
pubmed-meshheading:16472607-Gene Expression Profiling,
pubmed-meshheading:16472607-Gene Silencing,
pubmed-meshheading:16472607-Genes, Reporter,
pubmed-meshheading:16472607-Humans,
pubmed-meshheading:16472607-Luciferases,
pubmed-meshheading:16472607-Mutation,
pubmed-meshheading:16472607-Nerve Tissue Proteins,
pubmed-meshheading:16472607-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:16472607-Pancreatic Neoplasms,
pubmed-meshheading:16472607-RNA, Neoplasm,
pubmed-meshheading:16472607-RNA, Small Interfering,
pubmed-meshheading:16472607-Serine Endopeptidases,
pubmed-meshheading:16472607-Transfection
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pubmed:year |
2006
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pubmed:articleTitle |
Differential and epigenetic gene expression profiling identifies frequent disruption of the RELN pathway in pancreatic cancers.
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pubmed:affiliation |
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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