16464173

Source:http://linkedlifedata.com/resource/pubmed/id/16464173

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0020538, umls-concept:C0086345, umls-concept:C0086418
pubmed:issue	3
pubmed:dateCreated	2006-2-8
pubmed:abstractText	EH (essential hypertension) is a major public health problem in many countries due to its high prevalence and its association with coronary heart disease, stroke, renal disease, peripheral vascular disease and other disorders. Epidemiological studies have demonstrated that EH is heritable. Owing to the fact that blood pressure is controlled by cardiac output and total peripheral resistance, many molecular pathways are believed to be involved in the disease. In this review, recent genetic studies investigating the molecular basis of EH, including different molecular pathways, will be highlighted.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7905731
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0143-5221
pubmed:author	pubmed-author:GongMaolianM, pubmed-author:HubnerNorbertN
pubmed:issnType	Print
pubmed:volume	110
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	315-26
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:16464173-Chromosome Mapping, pubmed-meshheading:16464173-Genetic Predisposition to Disease, pubmed-meshheading:16464173-Humans, pubmed-meshheading:16464173-Hypertension, pubmed-meshheading:16464173-Mutation, pubmed-meshheading:16464173-Renin-Angiotensin System
pubmed:year	2006
pubmed:articleTitle	Molecular genetics of human hypertension.
pubmed:affiliation	Max-Delbrück-Center for Molecular Medicine (MDC), Robert-Rössle-Strasse 10, 13092 Berlin, Germany.
pubmed:publicationType	Journal Article, Review, Research Support, Non-U.S. Gov't