|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0007634,
umls-concept:C0007785,
umls-concept:C0021757,
umls-concept:C0038250,
umls-concept:C0205102,
umls-concept:C0205365,
umls-concept:C0205390,
umls-concept:C0242767,
umls-concept:C0262950,
umls-concept:C0521390,
umls-concept:C0599766,
umls-concept:C0599851,
umls-concept:C1186763,
umls-concept:C1514485,
umls-concept:C1704419,
umls-concept:C1705165,
umls-concept:C2700061
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2006-2-7
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|
pubmed:abstractText |
Hematopoietic cytokines, granulocyte colony-stimulating factor (G-CSF), and stem cell factor (SCF) were reported to show a neuroprotective effect or to support neurogenesis. These cytokines also mobilize bone marrow (BM) cells into the brain, and the BM-derived cells differentiate into neuronal cells. We administered these hematopoietic cytokines after focal cerebral ischemia and assessed their effects and the therapeutic time window for neuronal regeneration.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1524-4539
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|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:day |
7
|
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pubmed:volume |
113
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
701-10
|
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16461843-Animals,
pubmed-meshheading:16461843-Bone Marrow Cells,
pubmed-meshheading:16461843-Brain,
pubmed-meshheading:16461843-Cell Differentiation,
pubmed-meshheading:16461843-Cell Movement,
pubmed-meshheading:16461843-Cell Proliferation,
pubmed-meshheading:16461843-Cerebral Infarction,
pubmed-meshheading:16461843-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:16461843-Hematopoietic Cell Growth Factors,
pubmed-meshheading:16461843-Hematopoietic Stem Cell Mobilization,
pubmed-meshheading:16461843-Infarction, Middle Cerebral Artery,
pubmed-meshheading:16461843-Mice,
pubmed-meshheading:16461843-Mice, Transgenic,
pubmed-meshheading:16461843-Neurons,
pubmed-meshheading:16461843-Stem Cell Factor,
pubmed-meshheading:16461843-Stem Cells,
pubmed-meshheading:16461843-Treatment Outcome
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|
pubmed:year |
2006
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|
pubmed:articleTitle |
Administration of hematopoietic cytokines in the subacute phase after cerebral infarction is effective for functional recovery facilitating proliferation of intrinsic neural stem/progenitor cells and transition of bone marrow-derived neuronal cells.
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|
pubmed:affiliation |
Division of Hematology, Department of Medicine, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa, Japan. hkawada@is.icc.u-tokai.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
