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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1991-7-17
|
| pubmed:abstractText |
The crystal structure of ribonuclease Ms*3'-guanylic acid complex has been determined by molecular replacement methods based on the known structure of ribonuclease T1. The pattern of hydrogen-bonds between the enzyme and the guanine base is similar to that discovered by Arni et al. [( 1988) J. Biol. Chem. 263, 15358-15368] in the crystal structure of ribonuclease T1*2'-guanylic acid complex. As for the possible general base in the trans-phosphorylation step of the catalysis, 0 epsilon 1 of Glu57 is within the hydrogen-bond distance (2.7 A) of the 2'-0 of the nucleotide while N epsilon 2 of His39 is significantly more distant (3.4 A) from the 2'-0.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0014-5793
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
3
|
| pubmed:volume |
283
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
207-9
|
| pubmed:dateRevised |
2008-8-19
|
| pubmed:meshHeading |
pubmed-meshheading:1646118-5'-Guanylic Acid,
pubmed-meshheading:1646118-Amino Acid Sequence,
pubmed-meshheading:1646118-Binding Sites,
pubmed-meshheading:1646118-Endoribonucleases,
pubmed-meshheading:1646118-Models, Molecular,
pubmed-meshheading:1646118-Molecular Sequence Data,
pubmed-meshheading:1646118-Protein Conformation,
pubmed-meshheading:1646118-Sequence Homology, Nucleic Acid,
pubmed-meshheading:1646118-X-Ray Diffraction
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Three-dimensional structure of ribonuclease Ms*3'-guanylic acid complex at 2.5 A resolution.
|
| pubmed:affiliation |
Faculty of Engineering, Nagaoka University of Technology, Niigato, Japan.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|