Linked Life Data

16456881

Source:http://linkedlifedata.com/resource/pubmed/id/16456881

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:16456881rdf:typepubmed:Citationlld:pubmed
pubmed-article:16456881lifeskim:mentionsumls-concept:C0027575lld:lifeskim
pubmed-article:16456881lifeskim:mentionsumls-concept:C0348801lld:lifeskim
pubmed-article:16456881lifeskim:mentionsumls-concept:C1622418lld:lifeskim
pubmed-article:16456881lifeskim:mentionsumls-concept:C1167331lld:lifeskim
pubmed-article:16456881lifeskim:mentionsumls-concept:C0596988lld:lifeskim
pubmed-article:16456881lifeskim:mentionsumls-concept:C0205470lld:lifeskim
pubmed-article:16456881lifeskim:mentionsumls-concept:C1707455lld:lifeskim
pubmed-article:16456881lifeskim:mentionsumls-concept:C1705241lld:lifeskim
pubmed-article:16456881lifeskim:mentionsumls-concept:C0439097lld:lifeskim
pubmed-article:16456881lifeskim:mentionsumls-concept:C1547348lld:lifeskim
pubmed-article:16456881lifeskim:mentionsumls-concept:C0441836lld:lifeskim
pubmed-article:16456881pubmed:issue6lld:pubmed
pubmed-article:16456881pubmed:dateCreated2006-3-13lld:pubmed
pubmed-article:16456881pubmed:abstractTextWe compared the proteome of detergent-derived group B Neisseria meningitidis (MenB) outer membrane vesicles (DOMVs) with the proteome of outer membrane vesicles (m-OMVs) spontaneously released into culture supernatant by MenB delta gna33, a mutant in which the gene coding for a lytic transglycosylase homologous to the E. coli MltA was deleted. In total, 138 proteins were identified in DOMVs by 1- and 2-DE coupled with MS; 64% of these proteins belonged to the inner membrane and cytoplasmic compartments. By contrast, most of the 60 proteins of m-OMVs were classified by PSORT as outer membrane proteins. When tested for their capacity to elicit bactericidal antibodies, m-OMVs elicited a broad protective activity against a large panel of MenB strains. Therefore, the identification of mutations capable of conferring an OMV-releasing phenotype in bacteria may represent an attractive approach to study bacterial membrane composition and organization, and to design new efficacious vaccine formulations.lld:pubmed
pubmed-article:16456881pubmed:languageenglld:pubmed
pubmed-article:16456881pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16456881pubmed:citationSubsetIMlld:pubmed
pubmed-article:16456881pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16456881pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16456881pubmed:statusMEDLINElld:pubmed
pubmed-article:16456881pubmed:monthMarlld:pubmed
pubmed-article:16456881pubmed:issn1615-9853lld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:LDDlld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:NoraisNathali...lld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:GaragusoIgnaz...lld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:GrandiGuidoGlld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:Adu-BobieJean...lld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:GiulianiMarzi...lld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:PizzaMariagra...lld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:BiolchiAlessi...lld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:TaddeiAnna...lld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:FerrariGerman...lld:pubmed
pubmed-article:16456881pubmed:authorpubmed-author:DoroFrancesco...lld:pubmed
pubmed-article:16456881pubmed:issnTypePrintlld:pubmed
pubmed-article:16456881pubmed:volume6lld:pubmed
pubmed-article:16456881pubmed:ownerNLMlld:pubmed
pubmed-article:16456881pubmed:authorsCompleteYlld:pubmed
pubmed-article:16456881pubmed:pagination1856-66lld:pubmed
pubmed-article:16456881pubmed:dateRevised2006-11-15lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:meshHeadingpubmed-meshheading:16456881...lld:pubmed
pubmed-article:16456881pubmed:year2006lld:pubmed
pubmed-article:16456881pubmed:articleTitleOuter membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles.lld:pubmed
pubmed-article:16456881pubmed:affiliationBiochemistry and Molecular Biology Unit, Chiron Vaccines, Siena, Italy.lld:pubmed
pubmed-article:16456881pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16456881pubmed:publicationTypeComparative Studylld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16456881lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16456881lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16456881lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16456881lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16456881lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16456881lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16456881lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16456881lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16456881lld:pubmed