Source:http://linkedlifedata.com/resource/pubmed/id/16442355
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2006-1-30
|
pubmed:abstractText |
Left ventricular (LV) diastolic function is an important predictor of morbidity and mortality after acute myocardial infarction (AMI). We evaluated the role of diastolic function in predicting in-hospital events and LV ejection fraction (EF) 6 months after a first AMI that was treated with primary percutaneous coronary intervention (PCI). We prospectively enrolled 59 consecutive patients who were 60 +/- 15 years of age (48 men), presented at our institution with their first AMI, and were treated with primary PCI. Patients underwent 2-dimensional and Doppler echocardiography, including tissue Doppler imaging of 6 basal mitral annular regions within 24 hours after primary PCI and were followed until discharge. Clinical and echocardiographic variables at index AMI were compared with a combined end point of cardiac death, ventricular tachycardia, congestive heart failure, or emergency in-hospital surgical revascularization. Follow-up echocardiographic assessment was performed at 6 months in 24 patients. During hospitalization, 3 patients died, 7 developed congestive heart failure, 4 had ventricular tachycardia, and 1 required emergency surgical revascularization. Stepwise logistic regression analysis showed the ratio of early mitral inflow diastolic filling wave (E) to peak early diastolic velocity of non-infarct-related mitral annulus (p < 0.01) (E') and mitral inflow E-wave deceleration time (p < 0.02) to be independent predictors of in-hospital cardiac events (generalized R2 = 0.66). In a stepwise multiple linear regression model, independent predictors of follow-up LVEF were mitral inflow deceleration time (R2 = 0.39, p = 0.002), baseline LVEF (R2 = 0.54, p < 0.02), and mitral inflow peak early velocity/mitral annular peak early velocity (or E/E') of infarct annulus (R2 = 0.66, p = 0.02). In conclusion, in patients who are treated with primary PCI for a first AMI, E/E' velocity ratio and mitral inflow E-wave deceleration time are strong predictors of in-hospital cardiac events and of LVEF at 6-month follow-up.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0002-9149
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
97
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
160-6
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:16442355-Aged,
pubmed-meshheading:16442355-Aged, 80 and over,
pubmed-meshheading:16442355-Angioplasty, Balloon, Coronary,
pubmed-meshheading:16442355-Coronary Angiography,
pubmed-meshheading:16442355-Diastole,
pubmed-meshheading:16442355-Echocardiography, Doppler,
pubmed-meshheading:16442355-Female,
pubmed-meshheading:16442355-Humans,
pubmed-meshheading:16442355-Male,
pubmed-meshheading:16442355-Middle Aged,
pubmed-meshheading:16442355-Multivariate Analysis,
pubmed-meshheading:16442355-Myocardial Infarction,
pubmed-meshheading:16442355-Prognosis,
pubmed-meshheading:16442355-Stroke Volume,
pubmed-meshheading:16442355-Systole,
pubmed-meshheading:16442355-Treatment Outcome,
pubmed-meshheading:16442355-Ventricular Function, Left
|
pubmed:year |
2006
|
pubmed:articleTitle |
Comparison of usefulness of left ventricular diastolic versus systolic function as a predictor of outcome following primary percutaneous coronary angioplasty for acute myocardial infarction.
|
pubmed:affiliation |
The Cedars-Sinai Medical Center, University of California Los Angeles School of Medicine, Los Angeles, California, USA. tasneem.naqvi@cshs.org
|
pubmed:publicationType |
Journal Article,
Comparative Study
|