| pubmed-article:16436889 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16436889 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:16436889 | lifeskim:mentions | umls-concept:C0019010 | lld:lifeskim |
| pubmed-article:16436889 | lifeskim:mentions | umls-concept:C0681842 | lld:lifeskim |
| pubmed-article:16436889 | lifeskim:mentions | umls-concept:C0449446 | lld:lifeskim |
| pubmed-article:16436889 | lifeskim:mentions | umls-concept:C0814225 | lld:lifeskim |
| pubmed-article:16436889 | lifeskim:mentions | umls-concept:C0010216 | lld:lifeskim |
| pubmed-article:16436889 | lifeskim:mentions | umls-concept:C0205124 | lld:lifeskim |
| pubmed-article:16436889 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16436889 | pubmed:dateCreated | 2006-1-26 | lld:pubmed |
| pubmed-article:16436889 | pubmed:abstractText | A volume-displacement counterpulsation device (CPD) intended for chronic implantation via a superficial surgical approach is proposed. The CPD is a pneumatically driven sac that fills during native heart systole and empties during diastole through a single, valveless cannula anastomosed to the subclavian artery. Computer simulation was performed to predict and compare the physiological responses of the CPD to the intraaortic balloon pump (IABP) in a clinically relevant model of early stage heart failure. The effect of device stroke volume (0-50 ml) and control modes (timing, duration, morphology) on landmark hemodynamic parameters and the LV pressure-volume relationship were investigated. Simulation results predicted that the CPD would provide hemodynamic benefits comparable to an IABP as evidenced by up to 25% augmentation of peak diastolic aortic pressure, which increases diastolic coronary perfusion by up to 34%. The CPD may also provide up to 34% reduction in LV end-diastolic pressure and 12% reduction in peak systolic aortic pressure, lowering LV workload by up to 26% and increasing cardiac output by up to 10%. This study demonstrated that the superficial CPD technique may be used acutely to achieve similar improvements in hemodynamic function as the IABP in early stage heart failure patients. | lld:pubmed |
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| pubmed-article:16436889 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16436889 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16436889 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16436889 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16436889 | pubmed:issn | 1058-2916 | lld:pubmed |
| pubmed-article:16436889 | pubmed:author | pubmed-author:SpencePaul... | lld:pubmed |
| pubmed-article:16436889 | pubmed:author | pubmed-author:PantalosGeorg... | lld:pubmed |
| pubmed-article:16436889 | pubmed:author | pubmed-author:GiridharanGur... | lld:pubmed |
| pubmed-article:16436889 | pubmed:author | pubmed-author:LitwakKenneth... | lld:pubmed |
| pubmed-article:16436889 | pubmed:author | pubmed-author:KoenigSteven... | lld:pubmed |
| pubmed-article:16436889 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16436889 | pubmed:volume | 52 | lld:pubmed |
| pubmed-article:16436889 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16436889 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16436889 | pubmed:pagination | 39-46 | lld:pubmed |
| pubmed-article:16436889 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
| pubmed-article:16436889 | pubmed:meshHeading | pubmed-meshheading:16436889... | lld:pubmed |
| pubmed-article:16436889 | pubmed:meshHeading | pubmed-meshheading:16436889... | lld:pubmed |
| pubmed-article:16436889 | pubmed:meshHeading | pubmed-meshheading:16436889... | lld:pubmed |
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| pubmed-article:16436889 | pubmed:meshHeading | pubmed-meshheading:16436889... | lld:pubmed |
| pubmed-article:16436889 | pubmed:meshHeading | pubmed-meshheading:16436889... | lld:pubmed |
| pubmed-article:16436889 | pubmed:meshHeading | pubmed-meshheading:16436889... | lld:pubmed |
| pubmed-article:16436889 | pubmed:meshHeading | pubmed-meshheading:16436889... | lld:pubmed |
| pubmed-article:16436889 | pubmed:meshHeading | pubmed-meshheading:16436889... | lld:pubmed |
| pubmed-article:16436889 | pubmed:articleTitle | Predicted hemodynamic benefits of counterpulsation therapy using a superficial surgical approach. | lld:pubmed |
| pubmed-article:16436889 | pubmed:affiliation | Cardiovascular Innovation Institute, Departments of Surgery and Bioengineering, University of Louisville, 500 South Floyd Street, Louisville, KY 40202, USA. | lld:pubmed |
| pubmed-article:16436889 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16436889 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:16436889 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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