| pubmed-article:16423698 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16423698 | lifeskim:mentions | umls-concept:C0025663 | lld:lifeskim |
| pubmed-article:16423698 | lifeskim:mentions | umls-concept:C0039062 | lld:lifeskim |
| pubmed-article:16423698 | lifeskim:mentions | umls-concept:C0019564 | lld:lifeskim |
| pubmed-article:16423698 | lifeskim:mentions | umls-concept:C0033105 | lld:lifeskim |
| pubmed-article:16423698 | lifeskim:mentions | umls-concept:C0022702 | lld:lifeskim |
| pubmed-article:16423698 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:16423698 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:16423698 | lifeskim:mentions | umls-concept:C1709937 | lld:lifeskim |
| pubmed-article:16423698 | lifeskim:mentions | umls-concept:C2699072 | lld:lifeskim |
| pubmed-article:16423698 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:16423698 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:16423698 | pubmed:dateCreated | 2006-1-20 | lld:pubmed |
| pubmed-article:16423698 | pubmed:abstractText | The kinetics of exo-endocytotic recycling could restrict information transfer at central synapses if neurotransmission were entirely reliant on classical full-collapse fusion. Nonclassical fusion retrieval by kiss-and-run would be kinetically advantageous but remains controversial. We used a hydrophilic quencher, bromophenol blue (BPB), to help detect nonclassical events. Upon stimulation, extracellular BPB entered synaptic vesicles and quenched FM1-43 fluorescence, indicating retention of FM dye beyond first fusion. BPB also quenched fluorescence of VAMP (synaptobrevin-2)-EGFP, thus indicating the timing of first fusion of vesicles in the total recycling pool. Comparison with FM dye destaining revealed that kiss-and-run strongly prevailed over full-collapse fusion at low frequency, giving way to a near-even balance at high frequency. Quickening of kiss-and-run vesicle reuse was also observed at higher frequency in the average single vesicle fluorescence response. Kiss-and-run and reuse could enable hippocampal nerve terminals to conserve scarce vesicular resources when responding to widely varying input patterns. | lld:pubmed |
| pubmed-article:16423698 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16423698 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16423698 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16423698 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16423698 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16423698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16423698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16423698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16423698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16423698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16423698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16423698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16423698 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16423698 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:16423698 | pubmed:issn | 0896-6273 | lld:pubmed |
| pubmed-article:16423698 | pubmed:author | pubmed-author:ChoiSukwooS | lld:pubmed |
| pubmed-article:16423698 | pubmed:author | pubmed-author:TsienRichard... | lld:pubmed |
| pubmed-article:16423698 | pubmed:author | pubmed-author:HarataNobutos... | lld:pubmed |
| pubmed-article:16423698 | pubmed:author | pubmed-author:PyleJason LJL | lld:pubmed |
| pubmed-article:16423698 | pubmed:author | pubmed-author:AravanisAlexa... | lld:pubmed |
| pubmed-article:16423698 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16423698 | pubmed:day | 19 | lld:pubmed |
| pubmed-article:16423698 | pubmed:volume | 49 | lld:pubmed |
| pubmed-article:16423698 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16423698 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16423698 | pubmed:pagination | 243-56 | lld:pubmed |
| pubmed-article:16423698 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:meshHeading | pubmed-meshheading:16423698... | lld:pubmed |
| pubmed-article:16423698 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16423698 | pubmed:articleTitle | Frequency-dependent kinetics and prevalence of kiss-and-run and reuse at hippocampal synapses studied with novel quenching methods. | lld:pubmed |
| pubmed-article:16423698 | pubmed:affiliation | Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, USA. | lld:pubmed |
| pubmed-article:16423698 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16423698 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16423698 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16423698 | lld:pubmed |
