rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
2006-1-12
|
pubmed:abstractText |
A 70-year-old Japanese-American woman who had never smoked was diagnosed with stage IV non-small-cell lung cancer with rib metastases. She had previously been well and she had no family history of malignancy. While receiving treatment with erlotinib, an epidermal growth factor receptor small-molecule inhibitor, she progressed and developed new brain metastases. She failed further chemotherapy treatments and subsequently developed extensive symptomatic leptomeningeal carcinomatosis associated with diplopia, hemiparesis, weight loss, and incontinence.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1743-4254
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
3
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
50-7; quiz 1 p following 57
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:16407879-Adenocarcinoma,
pubmed-meshheading:16407879-Aged,
pubmed-meshheading:16407879-Bone Neoplasms,
pubmed-meshheading:16407879-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:16407879-Female,
pubmed-meshheading:16407879-Humans,
pubmed-meshheading:16407879-Meningeal Neoplasms,
pubmed-meshheading:16407879-Mutation,
pubmed-meshheading:16407879-Quinazolines,
pubmed-meshheading:16407879-Receptor, Epidermal Growth Factor,
pubmed-meshheading:16407879-Ribs,
pubmed-meshheading:16407879-Treatment Failure
|
pubmed:year |
2006
|
pubmed:articleTitle |
Gefitinib response of erlotinib-refractory lung cancer involving meninges--role of EGFR mutation.
|
pubmed:affiliation |
Section of Hematology-Oncology, University of Chicago, Chicago, IL, USA.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural,
Research Support, N.I.H., Intramural
|