Source:http://linkedlifedata.com/resource/pubmed/id/16406869
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2006-1-12
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pubmed:abstractText |
WX-G250 is a chimeric monoclonal antibody that binds to carbonic anhydrase IX(G250/MN), which is present on greater than 95% of RCCs of the clear cell subtype. The suggested working mechanism of WX-G250 is by ADCC. Because the number of activated ADCC effector cells can be increased by a low dose interleukin-2 pulsing schedule, a multicenter study was initiated to investigate whether WX-G250 combined with LD-IL-2 could lead to an improved clinical outcome in patients with progressive RCC.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-5347
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
175
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57-62
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pubmed:dateRevised |
2011-7-29
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pubmed:meshHeading |
pubmed-meshheading:16406869-Adult,
pubmed-meshheading:16406869-Aged,
pubmed-meshheading:16406869-Antibodies, Monoclonal,
pubmed-meshheading:16406869-Carcinoma, Renal Cell,
pubmed-meshheading:16406869-Disease Progression,
pubmed-meshheading:16406869-Drug Therapy, Combination,
pubmed-meshheading:16406869-Female,
pubmed-meshheading:16406869-Humans,
pubmed-meshheading:16406869-Interleukin-2,
pubmed-meshheading:16406869-Kidney Neoplasms,
pubmed-meshheading:16406869-Male,
pubmed-meshheading:16406869-Middle Aged,
pubmed-meshheading:16406869-Prospective Studies
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pubmed:year |
2006
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pubmed:articleTitle |
A clinical trial with chimeric monoclonal antibody WX-G250 and low dose interleukin-2 pulsing scheme for advanced renal cell carcinoma.
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pubmed:affiliation |
Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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