|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0026882,
umls-concept:C0029005,
umls-concept:C0034678,
umls-concept:C0238463,
umls-concept:C0332197,
umls-concept:C0337810,
umls-concept:C0599755,
umls-concept:C0812241,
umls-concept:C1285573,
umls-concept:C1511790,
umls-concept:C1512456
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2006-1-11
|
|
pubmed:abstractText |
The genes RET and RAS, and more recently BRAF, have been shown to be frequently mutated in human papillary thyroid carcinomas (PTC). The aim of this study was to genotype for these mutations a cohort of thyroid tumours collected at our institutions.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0300-0664
|
|
pubmed:author |
pubmed-author:AveniaNicolaN,
pubmed-author:BarbiFlaviaF,
pubmed-author:CartaClaudioC,
pubmed-author:CavaliereAntonioA,
pubmed-author:MacchiaruloAntonioA,
pubmed-author:MonacelliMassimoM,
pubmed-author:MorettiSoniaS,
pubmed-author:PasseriLuciaL,
pubmed-author:PuxedduEfisioE,
pubmed-author:SanteusanioFaustoF,
pubmed-author:TartagliaMarcoM
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
64
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
105-9
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:16402937-Adult,
pubmed-meshheading:16402937-Aged,
pubmed-meshheading:16402937-Carcinoma, Papillary,
pubmed-meshheading:16402937-Cohort Studies,
pubmed-meshheading:16402937-DNA Mutational Analysis,
pubmed-meshheading:16402937-Gene Frequency,
pubmed-meshheading:16402937-Gene Rearrangement,
pubmed-meshheading:16402937-Genetic Markers,
pubmed-meshheading:16402937-Genotype,
pubmed-meshheading:16402937-Humans,
pubmed-meshheading:16402937-Middle Aged,
pubmed-meshheading:16402937-Mutation,
pubmed-meshheading:16402937-Proto-Oncogene Proteins B-raf,
pubmed-meshheading:16402937-Proto-Oncogene Proteins c-ret,
pubmed-meshheading:16402937-Thyroid Neoplasms,
pubmed-meshheading:16402937-ras Proteins
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Genotyping of an Italian papillary thyroid carcinoma cohort revealed high prevalence of BRAF mutations, absence of RAS mutations and allowed the detection of a new mutation of BRAF oncoprotein (BRAF(V599lns)).
|
|
pubmed:affiliation |
Dipartimento di Biologia Cellulare e Neuroscienze, Istituto Superiore di Sanità, Rome, Italy.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
