| pubmed-article:16391231 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16391231 | lifeskim:mentions | umls-concept:C1837655 | lld:lifeskim |
| pubmed-article:16391231 | lifeskim:mentions | umls-concept:C0376571 | lld:lifeskim |
| pubmed-article:16391231 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:16391231 | lifeskim:mentions | umls-concept:C1155291 | lld:lifeskim |
| pubmed-article:16391231 | lifeskim:mentions | umls-concept:C1704241 | lld:lifeskim |
| pubmed-article:16391231 | lifeskim:mentions | umls-concept:C1880177 | lld:lifeskim |
| pubmed-article:16391231 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16391231 | pubmed:dateCreated | 2006-1-4 | lld:pubmed |
| pubmed-article:16391231 | pubmed:abstractText | The BRCA1 gene product and its stoichiometric binding partner, BARD1, play a vital role in the cellular response to DNA damage. However, how they acquire specific biochemical functions after DNA damage is poorly understood. Following exposure to genotoxic stress, DNA damage-specific interactions were observed between BRCA1/BARD1 and the DNA damage-response proteins, TopBP1 and Mre11/Rad50/NBS1. Two distinct DNA damage-dependent super complexes emerged; their activation was dependent, in part, on the actions of specific checkpoint kinases, and each super complex contributed to a distinctive aspect of the DNA damage response. The results support a new, multifactorial model that describes how genotoxic stress enables BRCA1 to execute a diverse set of DNA damage-response functions. | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16391231 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16391231 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16391231 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:16391231 | pubmed:issn | 0890-9369 | lld:pubmed |
| pubmed-article:16391231 | pubmed:author | pubmed-author:GreenbergRoge... | lld:pubmed |
| pubmed-article:16391231 | pubmed:author | pubmed-author:CantorSharon... | lld:pubmed |
| pubmed-article:16391231 | pubmed:author | pubmed-author:LivingstonDav... | lld:pubmed |
| pubmed-article:16391231 | pubmed:author | pubmed-author:NakataniYoshi... | lld:pubmed |
| pubmed-article:16391231 | pubmed:author | pubmed-author:PathaniaShail... | lld:pubmed |
| pubmed-article:16391231 | pubmed:author | pubmed-author:SobhianBijanB | lld:pubmed |
| pubmed-article:16391231 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16391231 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:16391231 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:16391231 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16391231 | pubmed:authorsComplete | Y | lld:pubmed |
