|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003316,
umls-concept:C0013018,
umls-concept:C0019728,
umls-concept:C0020792,
umls-concept:C0023418,
umls-concept:C0027708,
umls-concept:C0030705,
umls-concept:C0033684,
umls-concept:C0439064,
umls-concept:C0439851,
umls-concept:C0871261,
umls-concept:C1333899,
umls-concept:C1441547,
umls-concept:C1527169,
umls-concept:C1552596,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1880022,
umls-concept:C1947931,
umls-concept:C2911692
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|
pubmed:issue |
24 Pt 1
|
|
pubmed:dateCreated |
2005-12-19
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|
pubmed:abstractText |
Antigens derived from the Wilms' tumor (WT1) protein, which is overexpressed in leukemias, are attractive targets for immunotherapy. Four HLA-A*0201-restricted WT1-derived epitopes have been identified: WT37, WT126, WT187, and WT235. We determined the natural immunogenecity of these antigens in patients with hematologic malignancies and healthy donor.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Dec
|
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pubmed:issn |
1078-0432
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
15
|
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pubmed:volume |
11
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
8799-807
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16361568-Amino Acid Sequence,
pubmed-meshheading:16361568-CD8-Positive T-Lymphocytes,
pubmed-meshheading:16361568-Cell Line, Tumor,
pubmed-meshheading:16361568-HLA-A Antigens,
pubmed-meshheading:16361568-HLA-A2 Antigen,
pubmed-meshheading:16361568-Humans,
pubmed-meshheading:16361568-Immunodominant Epitopes,
pubmed-meshheading:16361568-Leukemia,
pubmed-meshheading:16361568-Molecular Sequence Data,
pubmed-meshheading:16361568-Peptides,
pubmed-meshheading:16361568-WT1 Proteins
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
T-cell responses directed against multiple HLA-A*0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: identification, quantification, and characterization.
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|
pubmed:affiliation |
Stem Cell Allotransplantation Section, Hematology Branch, National Heart Lung Blood Institute and Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland 20892, USA. rezvanik@nhlbi.nih.gov
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
