Source:http://linkedlifedata.com/resource/pubmed/id/16351673
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2005-12-14
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pubmed:abstractText |
We investigated the efficacy of a single vs. double steroid injections in the treatment of carpal tunnel syndrome (CTS) in a randomised double-blind controlled trial. Patients with idiopathic CTS were randomised into (i) one group receiving a baseline methylprednisolone acetate injection plus a saline injection 8 weeks later and (ii) a second group receiving methylprednisolone acetate injection at baseline and at 8 weeks. The primary outcome was the Global Symptom Score (GSS). Forty patients were recruited. By 40 weeks, the mean GSS improved from 25.6 to 14.1 in the single-injection group whereas from 26.7 to 12.6 in the reinjection group, but there was no significant difference in GSS between the two groups (p = 0.26). There were also no significant differences in terms of electrophysiological and functional outcomes. The results suggest that an additional steroid injection confers no added benefit to a single injection in terms of symptom relief.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1368-5031
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1417-21
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pubmed:dateRevised |
2007-2-14
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pubmed:meshHeading |
pubmed-meshheading:16351673-Analgesia,
pubmed-meshheading:16351673-Anti-Inflammatory Agents,
pubmed-meshheading:16351673-Carpal Tunnel Syndrome,
pubmed-meshheading:16351673-Double-Blind Method,
pubmed-meshheading:16351673-Female,
pubmed-meshheading:16351673-Humans,
pubmed-meshheading:16351673-Injections, Intramuscular,
pubmed-meshheading:16351673-Male,
pubmed-meshheading:16351673-Methylprednisolone,
pubmed-meshheading:16351673-Middle Aged,
pubmed-meshheading:16351673-Prospective Studies,
pubmed-meshheading:16351673-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
Single vs. two steroid injections for carpal tunnel syndrome: a randomised clinical trial.
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pubmed:affiliation |
Department of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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