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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
23
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pubmed:dateCreated |
2005-12-2
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pubmed:abstractText |
Fludarabine and cyclophosphamide is an effective combination but increases the risk of opportunistic infections due to depressed lymphocyte counts. In an attempt to preserve CD4 counts, we conducted a phase I, double-blind, placebo-controlled trial of recombinant interleukin-2 (IL-2) added to fludarabine and cyclophosphamide in patients with treatment-naive indolent lymphomas or chronic lymphocytic leukemia.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
8413-7
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pubmed:dateRevised |
2009-12-30
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pubmed:meshHeading |
pubmed-meshheading:16322303-Adult,
pubmed-meshheading:16322303-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16322303-CD4 Lymphocyte Count,
pubmed-meshheading:16322303-Cyclophosphamide,
pubmed-meshheading:16322303-Dose-Response Relationship, Drug,
pubmed-meshheading:16322303-Double-Blind Method,
pubmed-meshheading:16322303-Female,
pubmed-meshheading:16322303-Humans,
pubmed-meshheading:16322303-Injections, Subcutaneous,
pubmed-meshheading:16322303-Interleukin-2,
pubmed-meshheading:16322303-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:16322303-Longitudinal Studies,
pubmed-meshheading:16322303-Lymphoma, Follicular,
pubmed-meshheading:16322303-Male,
pubmed-meshheading:16322303-Middle Aged,
pubmed-meshheading:16322303-Vidarabine
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pubmed:year |
2005
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pubmed:articleTitle |
Phase I study of low-dose interleukin-2, fludarabine, and cyclophosphamide for previously untreated indolent lymphoma and chronic lymphocytic leukemia.
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pubmed:affiliation |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland 21231, USA. ykasamo1@jhmi.edu
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase I,
Research Support, N.I.H., Extramural
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