|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2006-4-21
|
|
pubmed:abstractText |
Vasoactive intestinal peptide (VIP) has demonstrated therapeutic effects in arthritis by inhibiting both innate and acquired immune responses. We investigated the potential effects of VIP in the regulation of Toll-like receptor (TLR) expression and function in synovial fibroblasts from patients with rheumatoid arthritis (RA) and osteoarthritis (OA).
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines,
http://linkedlifedata.com/resource/pubmed/chemical/MYD88 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Myeloid Differentiation Factor 88,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/TLR2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 2,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 4,
http://linkedlifedata.com/resource/pubmed/chemical/Vasoactive Intestinal Peptide
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1462-0324
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
45
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
527-32
|
|
pubmed:dateRevised |
2007-9-6
|
|
pubmed:meshHeading |
pubmed-meshheading:16319097-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:16319097-Arthritis, Rheumatoid,
pubmed-meshheading:16319097-Blotting, Western,
pubmed-meshheading:16319097-Cells, Cultured,
pubmed-meshheading:16319097-Chemokines,
pubmed-meshheading:16319097-Down-Regulation,
pubmed-meshheading:16319097-Fibroblasts,
pubmed-meshheading:16319097-Humans,
pubmed-meshheading:16319097-Myeloid Differentiation Factor 88,
pubmed-meshheading:16319097-Osteoarthritis, Knee,
pubmed-meshheading:16319097-RNA, Messenger,
pubmed-meshheading:16319097-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16319097-Synovial Membrane,
pubmed-meshheading:16319097-Toll-Like Receptor 2,
pubmed-meshheading:16319097-Toll-Like Receptor 4,
pubmed-meshheading:16319097-Vasoactive Intestinal Peptide
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
VIP down-regulates TLR4 expression and TLR4-mediated chemokine production in human rheumatoid synovial fibroblasts.
|
|
pubmed:affiliation |
Servicio de Reumatología, Hospital 12 de Octubre, Avda. de Córdoba s/n 28041, Madrid, Spain.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
