Source:http://linkedlifedata.com/resource/pubmed/id/16301974
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
19 Pt 2
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pubmed:dateCreated |
2005-11-22
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pubmed:abstractText |
Adequate initial anticoagulant treatment is required to prevent thrombus growth and recurrence. Intravenous unfractionated heparin is being replaced by low-molecular-weight heparin as the anticoagulant of choice for initial treatment of venous thromboembolism. Vitamin K antagonists remain the only oral anticoagulant available (target international normalized ratio: 2.5). The duration of therapy should be individualized according to the risk of recurrence and the risk of bleeding. Three months of treatment is usually adequate if thrombosis was provoked by a reversible risk factor such as surgery. For patients with unprovoked ("idiopathic") thrombosis, anticoagulant treatment for at least 6 months is indicated. For patients with a recurrence of venous thromboembolism or with an irreversible risk factor such as cancer, indefinite anticoagulant therapy is recommended. Long-term treatment with low-molecular-weight heparin is usually preferable for patients with active cancer. Systemic thrombolysis is indicated for patients with massive pulmonary embolism but controversy persists for those with isolated right ventricular dysfunction.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0755-4982
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1427-34
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading | |
pubmed:year |
2005
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pubmed:articleTitle |
[Treatment of venous thromboembolic disease].
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pubmed:affiliation |
Service de pneumologie, soins intensifs, Hôpital européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris, Faculté de médecine Paris V René Descartes, Paris. olivier.sanchez@hop.egp.aphp.fr
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pubmed:publicationType |
Journal Article,
English Abstract,
Review
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