Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2005-11-10
pubmed:abstractText
In current practice, optimal placement of deep-brain stimulators (DBSs) used to treat movement disorders in patients with Parkinson's disease and essential tremor is an iterative procedure. A target is chosen preoperatively based on anatomical landmarks identified on magnetic resonance images. This point is used as an initial position that is refined intraoperatively using both microelectrode recordings and macrostimulation. In this paper, we report on our current progress toward developing a system for the computer-assisted preoperative selection of target points and for the intraoperative adjustment of these points. The system consists of a deformable atlas of optimal target points that can be used to select automatically the preoperative target, of an electrophysiological atlas, and of an intraoperative interface. Results we have obtained show that automatic prediction of target points is an achievable goal. Our results also indicate that electrophysiological information could be used to resolve structures not visible in anatomic images, thus improving both preoperative and intraoperative guidance. Our intraoperative system has reached the stage of a working prototype and we compare targeting accuracy as well as the number of paths needed to reach the targets with our system and with the method in current clinical use.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0278-0062
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1469-78
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:16279083-Algorithms, pubmed-meshheading:16279083-Artificial Intelligence, pubmed-meshheading:16279083-Deep Brain Stimulation, pubmed-meshheading:16279083-Humans, pubmed-meshheading:16279083-Image Enhancement, pubmed-meshheading:16279083-Image Interpretation, Computer-Assisted, pubmed-meshheading:16279083-Imaging, Three-Dimensional, pubmed-meshheading:16279083-Intraoperative Care, pubmed-meshheading:16279083-Magnetic Resonance Imaging, pubmed-meshheading:16279083-Preoperative Care, pubmed-meshheading:16279083-Prosthesis Implantation, pubmed-meshheading:16279083-Reproducibility of Results, pubmed-meshheading:16279083-Sensitivity and Specificity, pubmed-meshheading:16279083-Subtraction Technique, pubmed-meshheading:16279083-Surgery, Computer-Assisted, pubmed-meshheading:16279083-Tomography, X-Ray Computed, pubmed-meshheading:16279083-User-Computer Interface
pubmed:year
2005
pubmed:articleTitle
Computer-aided placement of deep brain stimulators: from planning to intraoperative guidance.
pubmed:affiliation
Department of Electrical Engineering, Catholic University of Louvain (UCL), Louvain, Belgium. pierre-francois.dhaese@vanderbilt.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural