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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2005-11-8
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pubmed:abstractText |
Early-onset antisocial behavior accompanied by attention-deficit/hyperactivity disorder is a clinically severe variant of antisocial behavior that is associated with a particularly poor outcome. Identifying early predictors is thus important. Genetic and prenatal environmental risk factors and prefrontal cortical function are thought to contribute. Recent evidence suggests that prefrontal cortical function is influenced by a valine/methionine variant in the catechol O-methyltransferase (COMT) gene.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0003-990X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1275-8
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pubmed:dateRevised |
2009-11-3
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pubmed:meshHeading |
pubmed-meshheading:16275815-Adolescent,
pubmed-meshheading:16275815-Age Factors,
pubmed-meshheading:16275815-Age of Onset,
pubmed-meshheading:16275815-Antisocial Personality Disorder,
pubmed-meshheading:16275815-Attention Deficit Disorder with Hyperactivity,
pubmed-meshheading:16275815-Birth Weight,
pubmed-meshheading:16275815-Catechol O-Methyltransferase,
pubmed-meshheading:16275815-Child,
pubmed-meshheading:16275815-Child, Preschool,
pubmed-meshheading:16275815-Female,
pubmed-meshheading:16275815-Genetic Variation,
pubmed-meshheading:16275815-Genotype,
pubmed-meshheading:16275815-Humans,
pubmed-meshheading:16275815-Infant, Newborn,
pubmed-meshheading:16275815-Male,
pubmed-meshheading:16275815-Prefrontal Cortex,
pubmed-meshheading:16275815-Pregnancy,
pubmed-meshheading:16275815-Prenatal Exposure Delayed Effects,
pubmed-meshheading:16275815-Psychiatric Status Rating Scales,
pubmed-meshheading:16275815-Regression Analysis,
pubmed-meshheading:16275815-Risk Factors,
pubmed-meshheading:16275815-Valine
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pubmed:year |
2005
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pubmed:articleTitle |
Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder.
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pubmed:affiliation |
Department of Psychological Medicine, College of Medicine, School of Psychology, Cardiff University, Heath Park, Cardiff, Wales. thapar@cardiff.ac.uk
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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