Source:http://linkedlifedata.com/resource/pubmed/id/16270173
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2005-11-4
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pubmed:abstractText |
Chronic psychoemotional stress induced by negative experience of social defeats in intermale confrontations over a period of 30 days was found to lead to the development of anxious-depressive symptomatology in male mice. Cessation of the psychopathogenic conditions and placing of depressed animals in comfortable conditions for 1-2 weeks with females did not lift the pathological state. Individuals continued to show marked anxiety, a behavioral deficit, decreased communicativeness, and a high level of depressivity, as revealed by a variety of behavioral tests. Persistence of the resulting psychoemotional disturbance in these animals is evidence for the development and persistence of the behavioral pathology requiring drug treatment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0097-0549
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
917-24
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16270173-Analysis of Variance,
pubmed-meshheading:16270173-Animal Communication,
pubmed-meshheading:16270173-Animals,
pubmed-meshheading:16270173-Anxiety Disorders,
pubmed-meshheading:16270173-Behavior, Animal,
pubmed-meshheading:16270173-Conflict (Psychology),
pubmed-meshheading:16270173-Depression,
pubmed-meshheading:16270173-Disease Models, Animal,
pubmed-meshheading:16270173-Exploratory Behavior,
pubmed-meshheading:16270173-Female,
pubmed-meshheading:16270173-Male,
pubmed-meshheading:16270173-Maze Learning,
pubmed-meshheading:16270173-Mice,
pubmed-meshheading:16270173-Mice, Inbred C57BL,
pubmed-meshheading:16270173-Movement,
pubmed-meshheading:16270173-Reaction Time,
pubmed-meshheading:16270173-Statistics, Nonparametric
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pubmed:year |
2005
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pubmed:articleTitle |
A model of anxious depression: persistence of behavioral pathology.
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pubmed:affiliation |
Neurogenetics of Social Behavior Laboratory, Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, 10 Lavrent'ev Prospekt, 630090, Novosibirsk, Russia.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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