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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2005-11-2
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pubmed:abstractText |
Programmed death-1 (PD-1) mediates a negative signal and introduces tolerance for lymphocytes. Dysfunction of the PD-1 pathway is thought to result in autoimmune diseases such as rheumatoid arthritis (RA). To investigate the role of the PD-1/PD-L system in the pathology of Sjögren's syndrome (SS), we examined the expression of PD-1 and its ligand PD-L1 in salivary lymphocytes and salivary glands from patients with SS.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD274,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD80,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Apoptosis Regulatory Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/CD274 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/PDCD1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Programmed Cell Death 1 Receptor
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0315-162X
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pubmed:author |
pubmed-author:HatachiSaoriS,
pubmed-author:HonjoTasukuT,
pubmed-author:IwaiYoshikoY,
pubmed-author:KawanoSeijiS,
pubmed-author:KobayashiMasayaM,
pubmed-author:KomoriTakahideT,
pubmed-author:KumagaiShunichiS,
pubmed-author:KurimotoChiyoC,
pubmed-author:MaedaSakanS,
pubmed-author:MinatoNagahiroN,
pubmed-author:OkazakiTakuT,
pubmed-author:TanakaYoshimasaY
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pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2156-63
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16265694-Antigens, CD,
pubmed-meshheading:16265694-Antigens, CD274,
pubmed-meshheading:16265694-Antigens, CD80,
pubmed-meshheading:16265694-Antigens, Surface,
pubmed-meshheading:16265694-Antineoplastic Agents,
pubmed-meshheading:16265694-Apoptosis Regulatory Proteins,
pubmed-meshheading:16265694-Epithelial Cells,
pubmed-meshheading:16265694-Flow Cytometry,
pubmed-meshheading:16265694-Humans,
pubmed-meshheading:16265694-Immune Tolerance,
pubmed-meshheading:16265694-Interferon-gamma,
pubmed-meshheading:16265694-Membrane Glycoproteins,
pubmed-meshheading:16265694-Peptides,
pubmed-meshheading:16265694-Programmed Cell Death 1 Receptor,
pubmed-meshheading:16265694-Salivary Glands,
pubmed-meshheading:16265694-Sjogren's Syndrome,
pubmed-meshheading:16265694-T-Lymphocytes
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pubmed:year |
2005
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pubmed:articleTitle |
Enhanced expression of programmed death-1 (PD-1)/PD-L1 in salivary glands of patients with Sjögren's syndrome.
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pubmed:affiliation |
Department of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, Kobe, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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