Linked Life Data

1625601

Source:http://linkedlifedata.com/resource/pubmed/id/1625601

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-8-13
pubmed:abstractText
Embryonic genes are considered as a separate subset of genes with unique chromatin properties. There is a problem of defining the duration of perturbations of embryonic gene activity that has been chemically induced and the normal relatively longer lasting changes that occur during differentiation. This problem may be related to unique properties of the chromatin of embryonic genes. Methylation of DNA is thought to be only one level of control and the superstructure of chromatin involving heterochromatin is of equal importance to embryonic gene expression. Proto-oncogenes are considered to be embryonic type genes whose activities are regulated under the same mechanisms by which other embryonic genes are regulated. Control aspects are discussed in the light of i) repressor-derepressor and blocking-deblocking mechanisms, ii) activator genes, pseudogenes, LINES, SINES, v-type position effects, iii) effects of ethionine, and iv) steroid hormone effects especially with respect to a subset of repeated rRNA genes which are considered to be structured in embryonic type chromatin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0306-9877
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
245-9
pubmed:dateRevised
2008-8-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Generalizing the control process for embryonic genes.
pubmed:affiliation
Canadian Institute of Theoretical Biology, Nova Scotia.
pubmed:publicationType
Journal Article