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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2005-10-20
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pubmed:abstractText |
Disruptions of the anterior cruciate ligament (ACL) of the knee joint are common and are currently treated using ligament or tendon grafts. In this study, we tested the hypothesis that it is possible to fabricate an ACL construct in vitro using mesenchymal stem cells (MSC) in combination with an optimized collagen type I hydrogel, which is in clinical use for autologous chondrocyte transplantation (ACT).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1465-3249
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
447-55
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pubmed:dateRevised |
2008-4-24
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pubmed:meshHeading |
pubmed-meshheading:16236634-Animals,
pubmed-meshheading:16236634-Anterior Cruciate Ligament,
pubmed-meshheading:16236634-Biocompatible Materials,
pubmed-meshheading:16236634-Bioreactors,
pubmed-meshheading:16236634-Bone Marrow Cells,
pubmed-meshheading:16236634-Cattle,
pubmed-meshheading:16236634-Cell Culture Techniques,
pubmed-meshheading:16236634-Cells, Cultured,
pubmed-meshheading:16236634-Collagen Type I,
pubmed-meshheading:16236634-Collagen Type III,
pubmed-meshheading:16236634-Elastin,
pubmed-meshheading:16236634-Extracellular Matrix,
pubmed-meshheading:16236634-Fibronectins,
pubmed-meshheading:16236634-Histocytochemistry,
pubmed-meshheading:16236634-Humans,
pubmed-meshheading:16236634-Hydrogel,
pubmed-meshheading:16236634-Immunohistochemistry,
pubmed-meshheading:16236634-Knee Joint,
pubmed-meshheading:16236634-Materials Testing,
pubmed-meshheading:16236634-Mesenchymal Stem Cells,
pubmed-meshheading:16236634-Rats,
pubmed-meshheading:16236634-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16236634-Tissue Engineering
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pubmed:year |
2005
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pubmed:articleTitle |
Anterior cruciate ligament constructs fabricated from human mesenchymal stem cells in a collagen type I hydrogel.
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pubmed:affiliation |
Division of Tissue Engineering, Orthopaedic Center for Musculoskeletal Research, König-Ludwig-Haus, Julius-Maximilians-University, Würzburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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