Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-11-18
pubmed:abstractText
The discovery, SAR, and X-ray crystal structure of novel biarylaminoacyl-(S)-2-cyano-pyrrolidines and biarylaminoacylthiazolidines as potent inhibitors of dipeptidyl peptidase IV (DPP IV) are reported.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0960-894X
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
123-8
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:16236500-Animals, pubmed-meshheading:16236500-Antineoplastic Agents, pubmed-meshheading:16236500-Binding Sites, pubmed-meshheading:16236500-Blood Glucose, pubmed-meshheading:16236500-Caco-2 Cells, pubmed-meshheading:16236500-Chemistry, Pharmaceutical, pubmed-meshheading:16236500-Crystallography, X-Ray, pubmed-meshheading:16236500-Dipeptidyl Peptidase 4, pubmed-meshheading:16236500-Drug Design, pubmed-meshheading:16236500-Drug Screening Assays, Antitumor, pubmed-meshheading:16236500-Enzyme Inhibitors, pubmed-meshheading:16236500-Humans, pubmed-meshheading:16236500-Kinetics, pubmed-meshheading:16236500-Mice, pubmed-meshheading:16236500-Models, Chemical, pubmed-meshheading:16236500-Models, Molecular, pubmed-meshheading:16236500-Protease Inhibitors, pubmed-meshheading:16236500-Rats, pubmed-meshheading:16236500-Structure-Activity Relationship
pubmed:year
2006
pubmed:articleTitle
Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors.
pubmed:affiliation
Johnson and Johnson Pharmaceutical Research and Development, 665 Stockton Drive, Exton, PA 19341, USA.
pubmed:publicationType
Journal Article