16233454

Source:http://linkedlifedata.com/resource/pubmed/id/16233454

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0040652, umls-concept:C0085104, umls-concept:C0205314, umls-concept:C0679622, umls-concept:C1563732, umls-concept:C1956066
pubmed:issue	5
pubmed:dateCreated	2005-10-19
pubmed:abstractText	In search of an efficient transdermal drug delivery system (TDDS), a polyhydroxyalkanoate (PHA)-based system with a polyamidoamine dendrimer was examined. Tamsulosin was used as the model drug. The dendrimer was found to act as the weak enhancer. By adding the dendrimer, the dendrimer-containing PHA matrix achieved the clinically required amount of tamsulosin permeating through the skin model. This is also the first report of the application of PHA and dendrimer to the TDDS.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100888800
pubmed:status	PubMed-not-MEDLINE
pubmed:issn	1389-1723
pubmed:author	pubmed-author:HosakaYoshifumiY, pubmed-author:ItohYoshiakiY, pubmed-author:KawaseMasayaM, pubmed-author:KobayashiIchiroI, pubmed-author:MaedaIsamuI, pubmed-author:NakanoYoshihisaY, pubmed-author:UmedaFusakoF, pubmed-author:WangZhioxiongZ, pubmed-author:YagKiyohitoK, pubmed-author:YamakawaJunjiJ
pubmed:issnType	Print
pubmed:volume	95
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	541-3
pubmed:year	2003
pubmed:articleTitle	Novel transdermal drug delivery system with polyhydroxyalkanoate and starburst polyamidoamine dendrimer.
pubmed:affiliation	Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita 565-0871, Japan.
pubmed:publicationType	Journal Article