Linked Life Data

16227644

Source:http://linkedlifedata.com/resource/pubmed/id/16227644

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-10-17
pubmed:abstractText
The present study was designed to elucidate the antioxidant effect of (-)-epicatechin in streptozotocin (STZ)-induced diabetes in rats. Intraperitoneal administration of (-)-epicatechin at doses of 15 and 30 mg/kg to diabetic rats for a period of 35 days resulted in a significant decrease in blood glucose, thiobarbituric acid reactive substances and hydroperoxides and a significant increase in the concentration of glutathione and the activities of catalase, superoxide dismutase and glutathione peroxidase. (-)-Epicatechin at a dose of 30 mg/kg was found to be more effective. Administration of insulin to diabetic rats normalized the changes caused by STZ.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1734-1140
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
610-5
pubmed:dateRevised
2008-5-28
pubmed:meshHeading
pubmed:articleTitle
Effects of (-)-epicatechin, a flavonoid on lipid peroxidation and antioxidants in streptozotocin-induced diabetic liver, kidney and heart.
pubmed:affiliation
School of Chemical and Biotechnology, Shanmugha Arts, Science, Technology and Research Academy, Deemed University, Thirumalaisamudram, Thanjavur-613402, Tamil Nadu, India. Darstash@chem.sastra.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't