Source:http://linkedlifedata.com/resource/pubmed/id/16186813
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2005-9-30
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pubmed:abstractText |
We identified 15 regions of >1 Mb in the human genome composed of large ancient local duplications corresponding to gene deserts. We detected these intrachromosomal duplications in mouse and dog but not in chicken; they present as patches of similarity as low as 60%. These findings suggest that some human gene deserts originated from duplications of segments lacking genes in a mammalian common ancestor.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1061-4036
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1041-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16186813-Animals,
pubmed-meshheading:16186813-Dogs,
pubmed-meshheading:16186813-Evolution, Molecular,
pubmed-meshheading:16186813-Gene Duplication,
pubmed-meshheading:16186813-Genes, Duplicate,
pubmed-meshheading:16186813-Genome, Human,
pubmed-meshheading:16186813-Humans,
pubmed-meshheading:16186813-Mice
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pubmed:year |
2005
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pubmed:articleTitle |
Identification of large ancient duplications associated with human gene deserts.
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pubmed:affiliation |
Research Center for Advanced Science and Technology, Mitsubishi Research Institute, Inc., Tokyo 100-8141, Japan. takehiko@mri.co.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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