Source:http://linkedlifedata.com/resource/pubmed/id/16182602
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2005-10-18
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pubmed:abstractText |
Cell polarity plays an important role in plant development, but the mechanisms that first establish polarity cues remain obscure. By contrast, a flurry of information has recently emerged on the elaboration of cell shape from such unknown initial cell-polarity cues. Recent studies suggest that Rho-related GTPases in plants (ROPs), and their effector targets among the ROP-interactive CRIB motif-containing proteins (RICs), mediate two antagonistic pathways that have opposing action on cell polarization. ROP proteins appear to interact directly with upstream regulators of the ARP2/3 complex, which are conserved modulators of the actin cytoskeleton. ROP function is dependent on the class 1 ADP-ribosylation factors (ARFs), which are core components of the vesicle transport machinery that are also involved in the polar localization of PIN-FORMED (PIN) family auxin efflux facilitators.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ADP-Ribosylation Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Actin-Related Protein 2-3 Complex,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/rho GTP-Binding Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1369-5266
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
613-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16182602-ADP-Ribosylation Factors,
pubmed-meshheading:16182602-Actin-Related Protein 2-3 Complex,
pubmed-meshheading:16182602-Animals,
pubmed-meshheading:16182602-Cell Polarity,
pubmed-meshheading:16182602-Membrane Transport Proteins,
pubmed-meshheading:16182602-Protein Transport,
pubmed-meshheading:16182602-rho GTP-Binding Proteins
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pubmed:year |
2005
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pubmed:articleTitle |
Cell polarity: ROPing the ends together.
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pubmed:affiliation |
Department of Molecular Genetics, Utrecht University, Padualaan 8, 3584CH Utrecht, The Netherlands.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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