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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2005-9-22
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pubmed:abstractText |
Variants in the aldose reductase gene (AKR1B1) have been implicated in the development of diabetic retinopathy and nephropathy, with the most convincing data identifying a (CA)(n) repeat microsatellite allele (Z-2), which has a functional role in gene expression. In this study the association between polymorphisms in the AKR1B1 gene and diabetic neuropathy was investigated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0742-3071
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1315-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16176189-Adolescent,
pubmed-meshheading:16176189-Aldehyde Reductase,
pubmed-meshheading:16176189-Diabetes Mellitus, Type 1,
pubmed-meshheading:16176189-Diabetic Neuropathies,
pubmed-meshheading:16176189-Diabetic Retinopathy,
pubmed-meshheading:16176189-Genetic Predisposition to Disease,
pubmed-meshheading:16176189-Genotype,
pubmed-meshheading:16176189-Humans,
pubmed-meshheading:16176189-Microsatellite Repeats,
pubmed-meshheading:16176189-Polymorphism, Genetic,
pubmed-meshheading:16176189-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:16176189-Polymorphism, Single Nucleotide,
pubmed-meshheading:16176189-Pupil,
pubmed-meshheading:16176189-Reflex, Pupillary
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pubmed:year |
2005
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pubmed:articleTitle |
The association of aldose reductase gene (AKR1B1) polymorphisms with diabetic neuropathy in adolescents.
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pubmed:affiliation |
Institute of Endocrinology and Diabetes, Children's Hospital at Westmead, New South Wales, Australia. kimd@chw.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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