Source:http://linkedlifedata.com/resource/pubmed/id/16169721
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
22
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pubmed:dateCreated |
2005-10-5
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pubmed:abstractText |
A library of 30 trisubstituted pyrimidines were synthesized and evaluated for their in vitro antimalarial and antitubercular activity. Out of the 30 compounds synthesized, 23 compounds have shown in vitro antimalarial activity against Plasmodium falciparum in the range of 0.25-2 microg/mL and 16 compounds have shown antitubercular activity against Mycobacterium tuberculosis H37Ra, at a concentration of 25 microg/mL.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4923-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16169721-Animals,
pubmed-meshheading:16169721-Anti-Infective Agents,
pubmed-meshheading:16169721-Molecular Structure,
pubmed-meshheading:16169721-Mycobacterium tuberculosis,
pubmed-meshheading:16169721-Phenols,
pubmed-meshheading:16169721-Plasmodium falciparum,
pubmed-meshheading:16169721-Pyrimidines,
pubmed-meshheading:16169721-Structure-Activity Relationship
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pubmed:year |
2005
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pubmed:articleTitle |
Solid support synthesis of 6-aryl-2-substituted pyrimidin-4-yl phenols as anti-infective agents.
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pubmed:affiliation |
Division of Medicinal & Process Chemistry, Central Drug Research Institute, Lucknow 226001, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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