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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
1
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pubmed:dateCreated |
1992-7-31
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|
pubmed:abstractText |
This paper reports the preparation of the triazole ester 10, a methylenic bioisoster of an oxygenated compound A, effective inhibitor of the prostaglandin synthesis in vitro. Biological evaluation of 10 and of the corresponding acid 9 shows that the compounds maintain a good enzymatic inhibitory activity compared with indomethacin and aspirin.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jan
|
|
pubmed:issn |
0014-827X
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
91-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
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pubmed:year |
1992
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pubmed:articleTitle |
An 1,2,3-triazole derivative bioisoster of a potent in vitro prostaglandin synthesis inhibitor: preparation and biological activity.
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|
pubmed:affiliation |
Istituto di Chimica Farmaceutica e Tossicologica, Università di Pisa.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
