16160068

Source:http://linkedlifedata.com/resource/pubmed/id/16160068

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008976, umls-concept:C0017431, umls-concept:C0023981, umls-concept:C0034656, umls-concept:C0366686, umls-concept:C0473169, umls-concept:C1332829, umls-concept:C1516606, umls-concept:C1704686
pubmed:issue	3
pubmed:dateCreated	2005-9-14
pubmed:abstractText	Rapid genetic screening for cytochrome P450 (CYP) 2C9 variants may play a role in improving the efficacy and safety of warfarin in individuals with CYP2C9 variants. The feasibility of prospective CYP2C9 model-based warfarin dosing has not yet been assessed.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-10073515, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-10961881, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-11157641, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-11503010, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-11588061, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-11926893, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-12406644, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-12496751, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-12668507, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-12866628, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-15148533, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-15284536, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-8873220, http://linkedlifedata.com/resource/pubmed/commentcorrection/16160068-9005747
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101175887
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anticoagulants, http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases, http://linkedlifedata.com/resource/pubmed/chemical/CYP2C9 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/DNA, http://linkedlifedata.com/resource/pubmed/chemical/DNA Probes, http://linkedlifedata.com/resource/pubmed/chemical/Warfarin
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	1539-4182
pubmed:author	pubmed-author:BergRichard LRL, pubmed-author:BurmesterJames KJK, pubmed-author:CaldwellMichael DMD, pubmed-author:GlurichIngridI, pubmed-author:HillmanMichael AMA, pubmed-author:SchmelzerJohnJ, pubmed-author:VidailletHumberto JHJ, pubmed-author:WilkeRussell ARA, pubmed-author:YaleSteven HSH
pubmed:issnType	Print
pubmed:volume	3
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	137-45
pubmed:dateRevised	2010-3-23
pubmed:meshHeading	pubmed-meshheading:16160068-Aged, pubmed-meshheading:16160068-Anticoagulants, pubmed-meshheading:16160068-Aryl Hydrocarbon Hydroxylases, pubmed-meshheading:16160068-Blood Coagulation, pubmed-meshheading:16160068-DNA, pubmed-meshheading:16160068-DNA Probes, pubmed-meshheading:16160068-Dose-Response Relationship, Drug, pubmed-meshheading:16160068-Female, pubmed-meshheading:16160068-Follow-Up Studies, pubmed-meshheading:16160068-Genotype, pubmed-meshheading:16160068-Humans, pubmed-meshheading:16160068-Male, pubmed-meshheading:16160068-Models, Genetic, pubmed-meshheading:16160068-Pilot Projects, pubmed-meshheading:16160068-Point Mutation, pubmed-meshheading:16160068-Prospective Studies, pubmed-meshheading:16160068-Reproducibility of Results, pubmed-meshheading:16160068-Sensitivity and Specificity, pubmed-meshheading:16160068-Single-Blind Method, pubmed-meshheading:16160068-Thromboembolism, pubmed-meshheading:16160068-Warfarin
pubmed:year	2005
pubmed:articleTitle	A prospective, randomized pilot trial of model-based warfarin dose initiation using CYP2C9 genotype and clinical data.
pubmed:affiliation	Center for Human Genetics, Marshfield Clinic Research Foundation, 1000 North Oak Avenue, Marshfield, WI 54449, USA. wilke.russell@mcrf.mfldclin.edu
pubmed:publicationType	Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't