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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1992-7-28
|
| pubmed:abstractText |
Since July 1988, a total of 92 transbronchial biopsies (TBB) have been performed in 18 patients (aged 3-16 years). Twelve patients (67%) were heart-lung transplant (HLT) recipients undergoing surveillance for pulmonary graft rejection and infection. The remainder included immunocompromised patients at risk of opportunistic infections (n = 4), patients with fibrosing alveolitis (n = 1) and a collagen vascular disorder with suspected lung involvement (n = 1). TBB was performed through either a fiberoptic (n = 50) or a rigid (n = 41) bronchoscope, all under general anesthesia. On one occasion a cardiac bioptome was used through an endotracheal stent. The sensitivity of TBB for diagnosing acute and chronic rejection in HLT patients was 88% and 60%, respectively (specificity, 91% and 100%). Definitive diagnoses were made in 4 (67%) of the non-HLT group. Bronchoalveolar lavage (BAL) was performed during each procedure for microbiological and cytological examination. Thirty-four pathogenic organisms including Pseudomonas aeruginosa (16/34), Staphylococcus aureus (8/34), and Candida albicans (5/34) were isolated from BAL culture. Complications included pneumothorax (8%), transient pyrexia (7%), and dyspnea (2%).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
8755-6863
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
12
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
240-6
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:1614750-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:1614750-Adolescent,
pubmed-meshheading:1614750-Bacterial Infections,
pubmed-meshheading:1614750-Biopsy,
pubmed-meshheading:1614750-Bronchoscopes,
pubmed-meshheading:1614750-Bronchoscopy,
pubmed-meshheading:1614750-Child,
pubmed-meshheading:1614750-Child, Preschool,
pubmed-meshheading:1614750-Female,
pubmed-meshheading:1614750-Fiber Optic Technology,
pubmed-meshheading:1614750-Graft Rejection,
pubmed-meshheading:1614750-Humans,
pubmed-meshheading:1614750-Lung,
pubmed-meshheading:1614750-Lung Diseases,
pubmed-meshheading:1614750-Lung Diseases, Fungal,
pubmed-meshheading:1614750-Lung Neoplasms,
pubmed-meshheading:1614750-Lung Transplantation,
pubmed-meshheading:1614750-Male,
pubmed-meshheading:1614750-Pneumonia,
pubmed-meshheading:1614750-Postoperative Complications
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Technique and use of transbronchial biopsy in children and adolescents.
|
| pubmed:affiliation |
Hospital for Sick Children, London, United Kingdom.
|
| pubmed:publicationType |
Journal Article
|